e-Drug3D

1078

METHACYCLINE

DISCONTINUED

INN
METHACYCLINE

cas 914-00-1

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
TETRACYCLINES

ROUTE (list)

ORAL

ATC code

J01AA05

PK parameters

Target

TARGET RIBOSOME

DrugCentral

BACTERIAL 70S RIBOSOME INHIBITOR CHEMBL2363135 BACTERIAL 70S RIBOSOME 16S RIBOSOMAL RNA BACTERIA

Download SDF file

(2Z,4S,4aR,5S,5aR,12aS)-2-(amino-hydroxymethylidene)-4-dimethylamino-5,10,11,12a-tetrahydroxy-6-methylidene-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione

Formula:
C22H22N2O8

Calculated chemical properties:

MW 442.42
NB_atoms 32
XLogP -0.44
PSA 169.235
NB_HD 7
NB_HA 10
fsp3 0.32
Lipinski(0=no;1=yes) 0

FDA
NDA 060641 (pdf not found) INN (METHACYCLINE HYDROCHLORIDE) RONDOMYCIN (MEDPOINTE PHARM HLC) APPROVAL= - YEAR= 0 DISCONTINUED