e-Drug3D
1077
CYCLOSERINE
INN
CYCLOSERINE
cas 68-41-7
CLASS
ANTIINFECTIVES
TUBERCULOSTATIC
ANTIFUNGAL
ANTIBIOTIC
ANTIBACTERIAL
ANTIMETABOLITES
PEPTIDOGLYCAN BIOSYNTHESIS INHIBITOR
NMDA PARTIAL AGONIST
ROUTE (list)
ORAL
ATC code
J04AB01
PK parameters
Tmax 6 HOUR
t1/2 12 HOUR
Solubility
SOLUBLE IN WATER
TARGET NMDA RECEPTOR
D-ALANINE-D-ALANINE LIGASE
ALANINE RACEMASE
D-ALANINE-D-ALANINE LIGASE
ALANINE RACEMASE
PDB
1PB9 (CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION)
Ligand code = 4AX (link to the list of PDB complexes)
Download experimental 3D coordinates of 4AX with added hydrogens
ligase UNIPROT P9WP31 ddl
Alanine racemase UNIPROT P9WQA9 alr
Formula:
C3H6N2O2
Calculated chemical properties:
MW 102.10
NB_atoms 7
XLogP -1.62
PSA 70.372
NB_HD 3
NB_HA 4
fsp3 0.67
Lipinski(0=no;1=yes) 1
NB_atoms 7
XLogP -1.62
PSA 70.372
NB_HD 3
NB_HA 4
fsp3 0.67
Lipinski(0=no;1=yes) 1