e-Drug3D

1060

CEFTIBUTEN

DISCONTINUED

INN
CEFTIBUTEN

cas 97519-39-6

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS

ROUTE (list)

ORAL

ATC code

J01DD14

PK parameters

VD 32.5 LITER (65 KILOGRAM)
Cl 5 LITER / HOUR (65 KILOGRAM)
PPB 65 PERCENT
t1/2 2 HOUR

Target

TARGET PENICILLIN-BINDING PROTEIN

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)-5-hydroxy-5-oxopent-2-enoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate

Formula:
C15H14N4O6S2

Calculated chemical properties:

MW 408.43
NB_atoms 27
XLogP -2.72
PSA 152.504
NB_HD 3
NB_HA 10
fsp3 0.27
Lipinski(0=no;1=yes) 0

FDA
NDA 050685 (label) INN (CEFTIBUTEN DIHYDRATE) CEDAX (BURKE THERAP) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 050686 (label) INN (CEFTIBUTEN DIHYDRATE) CEDAX (BURKE THERAP) APPROVAL= AP YEAR= 1995 DISCONTINUED