e-Drug3D

1056

DIRITHROMYCIN

DISCONTINUED

INN
DIRITHROMYCIN

cas 62013-04-1

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
MACROLIDES

ROUTE (list)

ORAL

ATC code

J01FA13

PK parameters

Target

TARGET RIBOSOME

DrugCentral

Unknown

Download SDF file

(1S,2R,4R,5R,6S,7S,8R,11R,12R,15R,17S)-5-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-11-ethyl-4,12-dihydroxy-7-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-15-(2-methoxyethoxymethyl)-2,4,6,8,12,17-hexamethyl-10,14-dioxa-16-azabicyclo[11.3.1]heptadecan-9-one

Formula:
C42H78N2O14

Calculated chemical properties:

MW 835.06
NB_atoms 58
XLogP 2.20
PSA 147.944
NB_HD 5
NB_HA 16
fsp3 0.98
Lipinski(0=no;1=yes) 0

FDA
NDA 050678 (pdf not found) INN (DIRITHROMYCIN) DYNABAC (LILLY RES LABS) APPROVAL= AP YEAR= 1995 NEWMOLECULARENTITY DISCONTINUED