e-Drug3D

1048

CEFPIRAMIDE

DISCONTINUED

INN
CEFPIRAMIDE

cas 70797-11-4

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS

ROUTE (list)

INJECTION

ATC code

J01DD11

PK parameters

F 87.5 PERCENT
t1/2 5 HOUR (PMID3319507)

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(6R)-7-[[(2R)-2-(4-hydroxyphenyl)-2-[(6-methyl-4-oxo1H-pyridine-3-carbonyl)amino]acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Formula:
C25H24N8O7S2

Calculated chemical properties:

MW 611.65
NB_atoms 42
XLogP -1.42
PSA 202.262
NB_HD 4
NB_HA 15
fsp3 0.28
Lipinski(0=no;1=yes) 0

FDA
NDA 050633 (pdf not found) INN (CEFPIRAMIDE SODIUM) CEFPIRAMIDE SODIUM (WYETH AYERST) APPROVAL= AP YEAR= 1989 NEWMOLECULARENTITY DISCONTINUED