e-Drug3D

1047

cas 79350-37-1

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS

ROUTE (list)

ORAL

PK parameters

F 45 PERCENT
VD 15.6 LITER (65 KILOGRAM)
Cl 3.9 LITER / HOUR (65 KILOGRAM)
PPB 65 PERCENT
t1/2 4 HOUR

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

PDB
4KOU (CRYSTAL STRUCTURE OF A GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794 IN COMPLEX WITH CEFIXIME)

Ligand code = C04 (link to the list of PDB complexes)

Download experimental 3D coordinates of C04 with added hydrogens

MW 451.45
NB_atoms 30
XLogP -3.21
PSA 167.918
NB_HD 3
NB_HA 12
fsp3 0.25
Lipinski(0=no;1=yes) 0

FDA
NDA 050621 (pdf not found) INN (CEFIXIME) SUPRAX (LEDERLE) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 050622 (pdf not found) INN (CEFIXIME) SUPRAX (LEDERLE) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 065129 (pdf not found) INN (CEFIXIME) SUPRAX (LUPIN PHARMS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 065130 (pdf not found) INN (CEFIXIME) SUPRAX (LUPIN PHARMS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 065355 (pdf not found) INN (CEFIXIME) SUPRAX (LUPIN PHARMS) APPROVAL= AP YEAR= 2007
NDA 065380 (pdf not found) INN (CEFIXIME) SUPRAX (LUPIN LTD) APPROVAL= AP YEAR= 2010
NDA 203195 (pdf not found) INN (CEFIXIME) SUPRAX (LUPIN LTD) APPROVAL= AP YEAR= 2012
NDA 202091 (pdf not found) INN (CEFIXIME) SUPRAX (LUPIN LTD) APPROVAL= AP YEAR= 2013
NDA 204835 (pdf not found) INN (CEFIXIME) CEFIXIME (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2015
NDA 206938 (pdf not found) INN (CEFIXIME) CEFIXIME (AJENAT PHARMS) APPROVAL= AP YEAR= 2017
NDA 206939 (pdf not found) INN (CEFIXIME) CEFIXIME (AJENAT PHARMS) APPROVAL= AP YEAR= 2017
NDA 206144 (pdf not found) INN (CEFIXIME) CEFIXIME (CHARTWELL RX) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 210574 (pdf not found) INN (CEFIXIME) CEFIXIME (ALKEM LABS LTD) APPROVAL= AP YEAR= 2018
NDA 211775 (pdf not found) INN (CEFIXIME) CEFIXIME (ALKEM LABS LTD) APPROVAL= AP YEAR= 2021
NDA 206358 (pdf not found) INN (CEFIXIME) CEFIXIME (FDC LTD) APPROVAL= AP YEAR= 2024 DISCONTINUED