e-Drug3D

1046

cas 1404-90-6

CLASS

ANTIINFECTIVES
MACROLIDE
GLYCOPEPTIDE ANTIBACTERIALS
ANTIBACTERIAL
ANTIBIOTIC
INHIBITION OF CELL-WALL BIOSYNTHESIS

ROUTE (list)

ORAL INTRAVENOUS INJECTION

PK parameters

F POORLY ABSORBED
VD 35.1 LITER (65 KILOGRAM)
Cl 5.07 LITER / HOUR (65 KILOGRAM)
PPB 30 PERCENT
t1/2 6.5 HOUR

TARGET DNA

PDB
1PNV (TDP-EPI-VANCOSAMINYLTRANSFERASE GTFA FROM AMYCOLATOPSIS ORIENTALIS)

Ligand code = - (link to the list of PDB complexes)

Download experimental 3D coordinates of - with added hydrogens

MW 1448.24
NB_atoms 101
XLogP -1.23
PSA 477.831
NB_HD 20
NB_HA 33
fsp3 0.42
Lipinski(0=no;1=yes) 0

FDA
NDA 062845 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HCL (QUAD PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062956 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOR (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060180 (label) INN (VANCOMYCIN HYDROCHLORIDE) VANCOCIN HYDROCHLORIDE (STERISCIENCE) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 061667 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOCIN HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1983
NDA 050606 (label) INN (VANCOMYCIN HYDROCHLORIDE) VANCOCIN HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1986
NDA 062476 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOCIN HYDROCHLORIDE (STERISCIENCE) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 062682 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOLED (HIKMA) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 062663 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 1987
NDA 062716 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOCIN HYDROCHLORIDE (STERISCIENCE) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 062812 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOCIN HYDROCHLORIDE (STERISCIENCE) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 062879 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 062911 (label) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1988
NDA 062912 (label) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1988
NDA 063076 (label) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1990
NDA 062931 (label) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1992
NDA 062933 (label) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1992
NDA 050671 (label) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE IN PLASTIC CONTAINER (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1993
NDA 063321 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOLED (LEDERLE) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 065401 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (MEDIMETRIKS PHARMS) APPROVAL= AP YEAR= 2008
NDA 065397 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2008
NDA 065432 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2008
NDA 065455 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HOSPIRA INC) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 090250 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (PLANO PHARMS) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 091469 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 091554 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2011
NDA 065453 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 065478 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (ABON PHARMS LLC) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 065490 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (STRIDES PHARMA) APPROVAL= AP YEAR= 2012
NDA 065510 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 200837 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (SAGENT PHARMS) APPROVAL= AP YEAR= 2012
NDA 201048 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (PLANO PHARMS) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 202274 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (AVET LIFESCIENCES) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202275 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (AVET LIFESCIENCES) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202464 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (AVET LIFESCIENCES) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 090439 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (LUPIN LTD) APPROVAL= AP YEAR= 2015
NDA 091377 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (XELLIA PHARMS APS) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 201250 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 201251 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 204107 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2015
NDA 204125 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (XELLIA PHARMS APS) APPROVAL= AP YEAR= 2015
NDA 206243 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (XELLIA PHARMS APS) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 091532 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE IN PLASTIC CONTAINER (SAMSON MEDCL) APPROVAL= AP YEAR= 2016
NDA 205694 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (GLAND) APPROVAL= AP YEAR= 2016
NDA 205779 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (EUGIA PHARMA) APPROVAL= AP YEAR= 2016
NDA 205780 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (EUGIA PHARMA) APPROVAL= AP YEAR= 2016
NDA 208910 (label) INN (VANCOMYCIN HYDROCHLORIDE) FIRVANQ KIT (AZURITY) APPROVAL= AP YEAR= 2018
NDA 204360 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2018
NDA 206616 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HIKMA PHARMS) APPROVAL= AP YEAR= 2018
NDA 209481 (label) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2018
NDA 210729 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (ORIENT PHARMA CO LTD) APPROVAL= AP YEAR= 2019
NDA 211962 (label) INN (VANCOMYCIN HYDROCHLORIDE) TYZAVAN (HIKMA) APPROVAL= AP YEAR= 2019
NDA 212332 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (SLATE RUN PHARMA) APPROVAL= AP YEAR= 2019
NDA 203300 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2020
NDA 213895 (label) INN (VANCOMYCIN) VANCOMYCIN (HIKMA) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 215821 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (SLATE RUN PHARMA) APPROVAL= AP YEAR= 2021
NDA 213059 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (KNACK) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 216591 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (ASPIRO) APPROVAL= AP YEAR= 2022
NDA 214913 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (ALKEM LABS LTD) APPROVAL= AP YEAR= 2022
NDA 215195 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 215196 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 215197 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 210274 (label) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (ZHEJIANG NOVUS PHARM) APPROVAL= AP YEAR= 2023
NDA 215338 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (AMNEAL) APPROVAL= AP YEAR= 2023
NDA 217401 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (EUGIA PHARMA) APPROVAL= AP YEAR= 2023
NDA 217489 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2023
NDA 218140 (pdf not found) INN (VANCOMYCIN HYDROCHLORIDE) VANCOMYCIN HYDROCHLORIDE (GLAND) APPROVAL= AP YEAR= 2025