e-Drug3D

1045

CEFOTIAM

DISCONTINUED

INN
CEFOTIAM

cas 61622-34-2

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS

ROUTE (list)

INJECTION

ATC code

J01DC07

PK parameters

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-(2-dimethylaminoethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Formula:
C18H23N9O4S3

Calculated chemical properties:

MW 524.66
NB_atoms 34
XLogP -1.99
PSA 166.675
NB_HD 3
NB_HA 13
fsp3 0.50
Lipinski(0=no;1=yes) 0

FDA
NDA 050601 (pdf not found) INN (CEFOTIAM HYDROCHLORIDE) CERADON (TAKEDA) APPROVAL= AP YEAR= 1988 NEWMOLECULARENTITY DISCONTINUED