e-Drug3D

1041

cas 73384-59-5

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS

ROUTE (list)

INTRAMUSCULAR INTRAVENOUS INJECTION

PK parameters

VD 9.6 LITER
Cl 1 LITER / HOUR (65 KILOGRAM)
PPB 85 PERCENT
t1/2 7.25 LITER / HOUR

TARGET GAMMA-GLUTAMYLTRANSPEPTIDASE

PDB
5NZX (CRYSTAL STRUCTURE OF DNA CROSS-LINK REPAIR PROTEIN 1A IN COMPLEX WITH CEFTRIAXONE (ALTERNATIVE SITE))

Ligand code = 9F2 (link to the list of PDB complexes)

Download experimental 3D coordinates of 9F2 with added hydrogens

MW 553.61
NB_atoms 36
XLogP -2.95
PSA 195.933
NB_HD 4
NB_HA 15
fsp3 0.33
Lipinski(0=no;1=yes) 0

FDA
NDA 062510 (pdf not found) INN (CEFTRIAXONE SODIUM) ROCEPHIN (ROCHE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050585 (label) INN (CEFTRIAXONE SODIUM ; LIDOCAINE) ROCEPHIN KIT (HOFFMANN LA ROCHE) APPROVAL= AP YEAR= 1984 NEWMOLECULARENTITY DISCONTINUED
NDA 050624 (label) INN (CEFTRIAXONE SODIUM) ROCEPHIN W/ DEXTROSE IN PLASTIC CONTAINER (HOFFMANN LA ROCHE) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 062654 (pdf not found) INN (CEFTRIAXONE SODIUM) ROCEPHIN (HOFFMANN LA ROCHE) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 063239 (pdf not found) INN (CEFTRIAXONE SODIUM) ROCEPHIN (HOFFMANN LA ROCHE) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 065125 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (LUPIN) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 050796 (label) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE AND DEXTROSE IN DUPLEX CONTAINER (B BRAUN) APPROVAL= AP YEAR= 2005
NDA 065168 (label) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (SANDOZ) APPROVAL= AP YEAR= 2005
NDA 065169 (label) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (SANDOZ) APPROVAL= AP YEAR= 2005
NDA 065204 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (SANDOZ INC) APPROVAL= AP YEAR= 2005
NDA 065224 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE IN PLASTIC CONTAINER (BAXTER HLTHCARE) APPROVAL= AP YEAR= 2005
NDA 065230 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (HOSPIRA INC) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 065231 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (HOSPIRA INC) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 065232 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (HOSPIRA INC) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 065180 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 2006
NDA 065245 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065252 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065262 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (TEVA) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065263 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (LUPIN) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065274 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (TEVA) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 065227 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 065268 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (FACTA FARMA) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 065269 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (FACTA FARMA) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 065294 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (CEPHAZONE PHARMA) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 065391 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (WOCKHARDT BIO AG) APPROVAL= AP YEAR= 2007
NDA 065305 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2008
NDA 065328 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (ACS DOBFAR) APPROVAL= AP YEAR= 2008
NDA 065329 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (ACS DOBFAR) APPROVAL= AP YEAR= 2008
NDA 065342 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (HIKMA FARMACEUTICA) APPROVAL= AP YEAR= 2008
NDA 065465 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (BEDFORD) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 065475 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (BEDFORD) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 065504 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 065505 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 202563 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (HOSPIRA INC) APPROVAL= AP YEAR= 2012 DISCONTINUED
NDA 091068 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (AGILA SPECLTS) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 090057 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (SAMSON MEDCL) APPROVAL= AP YEAR= 2014
NDA 203702 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (QILU ANTIBIOTICS) APPROVAL= AP YEAR= 2016
NDA 091117 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE SODIUM (ANDA REPOSITORY) APPROVAL= AP YEAR= 2017
NDA 090701 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE SODIUM (HIKMA) APPROVAL= AP YEAR= 2017
NDA 091049 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (ASTRAL) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 209218 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (QILU ANTIBIOTICS) APPROVAL= AP YEAR= 2018
NDA 210197 (pdf not found) INN (CEFTRIAXONE SODIUM) CEFTRIAXONE (DEVA HOLDING AS) APPROVAL= AP YEAR= 2024 DISCONTINUED