e-Drug3D

1039

CEFONICID

DISCONTINUED

INN
CEFONICID

cas 61270-58-4

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
CEPHALOSPORINS

ROUTE (list)

INJECTION

ATC code

J01DC06

PK parameters

VD 455 LITER
Cl 87 LITER / HOUR
PPB 83 PERCENT (PMID3789691)
t1/2 5.1 HOUR

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(6R,7R)-7-[(2-hydroxy-2-phenylacetyl)amino]-8-oxo-3-[[1-(sulfomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Formula:
C18H18N6O8S3

Calculated chemical properties:

MW 541.59
NB_atoms 35
XLogP -2.25
PSA 203.786
NB_HD 3
NB_HA 14
fsp3 0.33
Lipinski(0=no;1=yes) 0

FDA
NDA 050579 (pdf not found) INN (CEFONICID SODIUM) MONOCID (GLAXOSMITHKLINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 063295 (pdf not found) INN (CEFONICID SODIUM) MONOCID (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1993 DISCONTINUED