e-Drug3D

1036

CEFMENOXIME

DISCONTINUED

INN
CEFMENOXIME

cas 65085-01-0

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS

ROUTE (list)

INJECTION

ATC code

J01DD05
S01AA31
S02AA18

PK parameters

VD 8.26 LITER
Cl 5 LITER / HOUR (EQN)
PPB 77 PERCENT
t1/2 1.14 HOUR (PMID6311084)

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Formula:
C16H17N9O5S3

Calculated chemical properties:

MW 510.59
NB_atoms 33
XLogP -2.20
PSA 176.421
NB_HD 3
NB_HA 14
fsp3 0.38
Lipinski(0=no;1=yes) 0

FDA
NDA 050571 (pdf not found) INN (CEFMENOXIME HYDROCHLORIDE) CEFMAX (TAP PHARM) APPROVAL= AP YEAR= 1987 NEWMOLECULARENTITY DISCONTINUED