e-Drug3D

1033

AZLOCILLIN

DISCONTINUED

INN
AZLOCILLIN

cas 37091-66-0

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
PENICILLINS

ROUTE (list)

INJECTION

ATC code

J01CA09

PK parameters

VD 17 LITER (65 KILOGRAM)
Cl 9.7 LITER / HOUR (65 KILOGRAM)
PPB 35 PERCENT
t1/2 1.2 HOUR

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Penicillin-binding protein UNIPROT Q07806 mrcA

Download SDF file

(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[[2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Formula:
C20H23N5O6S

Calculated chemical properties:

MW 460.50
NB_atoms 32
XLogP -1.24
PSA 144.01
NB_HD 3
NB_HA 11
fsp3 0.45
Lipinski(0=no;1=yes) 0

FDA
NDA 050562 (pdf not found) INN (AZLOCILLIN SODIUM) AZLIN (BAYER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062388 (pdf not found) INN (AZLOCILLIN SODIUM) AZLIN (BAYER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062417 (pdf not found) INN (AZLOCILLIN SODIUM) AZLIN (BAYER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED