e-Drug3D

1032

CEFTIZOXIME

DISCONTINUED

INN
CEFTIZOXIME

cas 68401-81-0

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS

ROUTE (list)

INJECTION

ATC code

J01DD07

PK parameters

VD 13 LITER (65 KILOGRAM)
Cl 8.2 LITER / HOUR (65 KILOGRAM)
PPB 28 PERCENT
t1/2 1.5 HOUR

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Formula:
C13H13N5O5S2

Calculated chemical properties:

MW 382.42
NB_atoms 25
XLogP -1.89
PSA 130.157
NB_HD 3
NB_HA 10
fsp3 0.31
Lipinski(0=no;1=yes) 1

FDA
NDA 050560 (pdf not found) INN (CEFTIZOXIME SODIUM) CEFIZOX (ASTELLAS) APPROVAL= AP YEAR= 1983 NEWMOLECULARENTITY DISCONTINUED
NDA 050589 (pdf not found) INN (CEFTIZOXIME SODIUM) CEFIZOX IN DEXTROSE 5% IN PLASTIC CONTAINER (ASTELLAS) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 063294 (pdf not found) INN (CEFTIZOXIME SODIUM) CEFIZOX (ASTELLAS) APPROVAL= AP YEAR= 1994 DISCONTINUED