e-Drug3D

1028

CEFORANIDE

DISCONTINUED

INN
CEFORANIDE

cas 60925-61-3

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS

ROUTE (list)

INJECTION

ATC code

J01DC11

PK parameters

VD 11 LITER (65 KILOGRAM)
Cl 2.6 LITER / HOUR (65 KILOGRAM)
PPB 81 PERCENT
t1/2 3 HOUR

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(6R,7R)-7-[[2-[2-(aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Formula:
C20H21N7O6S2

Calculated chemical properties:

MW 517.56
NB_atoms 35
XLogP -3.38
PSA 188.183
NB_HD 3
NB_HA 13
fsp3 0.35
Lipinski(0=no;1=yes) 0

FDA
NDA 062579 (pdf not found) INN (CEFORANIDE) PRECEF (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050554 (pdf not found) INN (CEFORANIDE) PRECEF (BRISTOL) APPROVAL= AP YEAR= 1984 NEWMOLECULARENTITY DISCONTINUED