e-Drug3D

1026

MOXALACTAM

DISCONTINUED

INN
MOXALACTAM

cas 64952-97-2

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC

ROUTE (list)

INJECTION

ATC code

J01DD06

PK parameters

VD 11 LITER (65 KILOGRAM)
Cl 2.8 LITER / HOUR (65 KILOGRAM)
PPB 61 PERCENT
t1/2 2.9 HOUR

Target

TARGET PENICILLIN-BINDING PROTEIN

DrugCentral

Peptidoglycan synthase FtsI UNIPROT P0AD68 ftsI

Penicillin-binding protein 1A UNIPROT P02918 mrcA

Download SDF file

5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, (6R,7R)-

Formula:
C20H20N6O9S

Calculated chemical properties:

MW 518.47
NB_atoms 36
XLogP -3.80
PSA 189.327
NB_HD 2
NB_HA 15
fsp3 0.35
Lipinski(0=no;1=yes) 0

FDA
NDA 050550 (pdf not found) INN (MOXALACTAM DISODIUM) MOXAM (LILLY) APPROVAL= - YEAR= 0 DISCONTINUED