e-Drug3D

1023

NETILMICIN

DISCONTINUED

INN
NETILMICIN

cas 56391-56-1

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
AMINOGLYCOSIDES
PROTEIN SYNTHESIS INHIBITORS

ROUTE (list)

INJECTION

ATC code

J01GB07
S01AA23

PK parameters

VD 4.7 LITER (65 KILOGRAM)
Cl 2.1 LITER / HOUR (65 KILOGRAM)
PPB 0 PERCENT
t1/2 3.2 HOUR

Target

TARGET 30S RIBOSOMAL PROTEIN S12

DrugCentral

Unknown

Download SDF file

(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4-amino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-6-ethylamino-2-hydroxycyclohexyl]oxy-5-methyl-4-methylaminooxane-3,5-diol

Formula:
C21H41N5O7

Calculated chemical properties:

MW 475.59
NB_atoms 33
XLogP -3.20
PSA 194.517
NB_HD 11
NB_HA 12
fsp3 0.90
Lipinski(0=no;1=yes) 0

FDA
NDA 050544 (pdf not found) INN (NETILMICIN SULFATE) NETROMYCIN (SCHERING) APPROVAL= AP YEAR= 1983 DISCONTINUED