e-Drug3D

1021

cas 53994-73-3

CLASS

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
CEPHALOSPORINS

ROUTE (list)

ORAL

PK parameters

F 85 PERCENT
Tmax 0.75 HOUR
PPB 37.5 PERCENT
t1/2 0.75 HOUR

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

PDB
7Q4X (CRYSTAL STRUCTURE OF EQUINE SERUM ALBUMIN IN COMPLEX WITH CEFACLOR)

Ligand code = 8XI (link to the list of PDB complexes)

Download experimental 3D coordinates of 8XI with added hydrogens

MW 366.80
NB_atoms 24
XLogP -0.71
PSA 101.884
NB_HD 3
NB_HA 7
fsp3 0.27
Lipinski(0=no;1=yes) 1

FDA
NDA 050521 (label) INN (CEFACLOR) CECLOR (LILLY) APPROVAL= AP YEAR= 1979 NEWMOLECULARENTITY DISCONTINUED
NDA 050522 (label) INN (CEFACLOR) CECLOR (LILLY) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 062205 (pdf not found) INN (CEFACLOR) CEFACLOR (CEPH INTL) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 062206 (pdf not found) INN (CEFACLOR) CEFACLOR (FACTA FARMA) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 064061 (pdf not found) INN (CEFACLOR) CEFACLOR (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064070 (pdf not found) INN (CEFACLOR) CEFACLOR (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064085 (pdf not found) INN (CEFACLOR) CEFACLOR (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064086 (pdf not found) INN (CEFACLOR) CEFACLOR (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064087 (pdf not found) INN (CEFACLOR) CEFACLOR (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064107 (pdf not found) INN (CEFACLOR) CEFACLOR (DAVA PHARMS INC) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064110 (pdf not found) INN (CEFACLOR) CEFACLOR (DAVA PHARMS INC) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064114 (pdf not found) INN (CEFACLOR) CEFACLOR (DAVA PHARMS INC) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064115 (pdf not found) INN (CEFACLOR) CEFACLOR (DAVA PHARMS INC) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064116 (pdf not found) INN (CEFACLOR) CEFACLOR (DAVA PHARMS INC) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 050673 (pdf not found) INN (CEFACLOR) CECLOR CD (LILLY) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 064081 (label) INN (CEFACLOR) CEFACLOR (TEVA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 064145 (pdf not found) INN (CEFACLOR) CEFACLOR (TEVA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 064148 (pdf not found) INN (CEFACLOR) CEFACLOR (CHARTWELL RX) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 064155 (pdf not found) INN (CEFACLOR) CEFACLOR (RANBAXY) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 064156 (pdf not found) INN (CEFACLOR) CEFACLOR (RANBAXY) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 064164 (pdf not found) INN (CEFACLOR) CEFACLOR (RANBAXY) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 064165 (pdf not found) INN (CEFACLOR) CEFACLOR (RANBAXY) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 064166 (pdf not found) INN (CEFACLOR) CEFACLOR (RANBAXY) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 064204 (pdf not found) INN (CEFACLOR) CEFACLOR (WATSON LABS INC) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 064205 (pdf not found) INN (CEFACLOR) CEFACLOR (WATSON LABS INC) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 064206 (pdf not found) INN (CEFACLOR) CEFACLOR (WATSON LABS INC) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 064207 (pdf not found) INN (CEFACLOR) CEFACLOR (WATSON LABS INC) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 065057 (pdf not found) INN (CEFACLOR) CEFACLOR (WORLD GEN) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 065058 (pdf not found) INN (CEFACLOR) CEFACLOR (TEVA) APPROVAL= AP YEAR= 2002
NDA 065092 (pdf not found) INN (CEFACLOR) RANICLOR (RANBAXY LABS LTD) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 065146 (pdf not found) INN (CEFACLOR) CEFACLOR (YUNG SHIN PHARM) APPROVAL= AP YEAR= 2004
NDA 065350 (pdf not found) INN (CEFACLOR) CEFACLOR (HIKMA) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 065412 (pdf not found) INN (CEFACLOR) CEFACLOR (YUNG SHIN PHARM) APPROVAL= AP YEAR= 2012