e-Drug3D

1017

NATAMYCIN

INN
NATAMYCIN

cas 7681-93-8

CLASS

ANTIINFECTIVES
ANTIFUNGAL AGENTS
ERGOSTEROL-SPECIFIC AND REVERSIBLE INHIBITION OF MEMBRANE TRANSPORT PROTEINS (PMID22733749)

ROUTE (list)

OPHTHALMIC

ATC code

A01AB10
A07AA03
D01AA02
G01AA02
S01AA10

PK parameters

Target

TARGET FUNGAL MEMBRANE TRANSPORT PROTEINS

DrugCentral

Unknown

Download SDF file

6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-.beta.-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-

Formula:
C33H47NO13

Calculated chemical properties:

MW 664.71
NB_atoms 47
XLogP -1.21
PSA 209.463
NB_HD 7
NB_HA 14
fsp3 0.64
Lipinski(0=no;1=yes) 0

FDA
NDA 050514 (label) INN (NATAMYCIN) NATACYN (HARROW EYE) APPROVAL= AP YEAR= 1978