e-Drug3D

1015

CEFAMANDOLE NAFATE

DISCONTINUED

INN
CEFAMANDOLE NAFATE

(has an active metabolite)

cas 42540-40-9

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
CEPHALOSPORINS

ROUTE (list)

INJECTION

ATC code

J01DC03

PK parameters

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(6R,7R)-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Formula:
C19H18N6O6S2

Calculated chemical properties:

MW 489.53
NB_atoms 33
XLogP -1.38
PSA 154.44
NB_HD 1
NB_HA 12
fsp3 0.32
Lipinski(0=no;1=yes) 0

FDA
NDA 050504 (pdf not found) INN (CEFAMANDOLE NAFATE) MANDOL (LILLY) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 062560 (pdf not found) INN (CEFAMANDOLE NAFATE) MANDOL (LILLY) APPROVAL= AP YEAR= 1985 DISCONTINUED