e-Drug3D

1014

TICARCILLIN

DISCONTINUED

INN
TICARCILLIN

cas 34787-01-4

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
PENICILLIN
ANTIBIOTIC

ROUTE (list)

INJECTION

ATC code

J01CA13
J01CR03

PK parameters

VD 10.4 LITER (65 KILOGRAM)
Cl 7 LITER / HOUR (65 KILOGRAM)
PPB 45 PERCENT
t1/2 1.1 HOUR

Solubility

VERY SOLUBLE IN WATER

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(2S,5R,6R)-6-[[(2R)-3-hydroxy-3-oxo-2-thiophen-3-ylpropanoyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Formula:
C15H16N2O6S2

Calculated chemical properties:

MW 382.42
NB_atoms 25
XLogP -2.12
PSA 119.31
NB_HD 1
NB_HA 8
fsp3 0.47
Lipinski(0=no;1=yes) 1

FDA
NDA 050497 (pdf not found) INN (TICARCILLIN DISODIUM) TICAR (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 050590 (label) INN (CLAVULANATE POTASSIUM ; TICARCILLIN DISODIUM) TIMENTIN (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 062690 (pdf not found) INN (TICARCILLIN DISODIUM) TICAR (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 062691 (pdf not found) INN (CLAVULANATE POTASSIUM ; TICARCILLIN DISODIUM) TIMENTIN (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 050658 (label) INN (CLAVULANATE POTASSIUM ; TICARCILLIN DISODIUM) TIMENTIN IN PLASTIC CONTAINER (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1989 DISCONTINUED