e-Drug3D

1010

cas 153-61-7

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC

ROUTE (list)

INJECTION

PK parameters

VD 4.5 LITER (65 KILOGRAM)
Cl 7 LITER / HOUR (65 KILOGRAM)
PPB 78 PERCENT
t1/2 0.95 HOUR

TARGET PENICILLIN-BINDING PROTEINS 1A/1B
D-ALANYL-D-ALANINE CARBOXYPEPTIDASE
BETA-LACTAMASE

PDB
4KOX (CRYSTAL STRUCTURE OF A GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794 IN COMPLEX WITH CEFALOTIN)

Ligand code = CLS (link to the list of PDB complexes)

Download experimental 3D coordinates of CLS with added hydrogens

MW 395.44
NB_atoms 26
XLogP -0.74
PSA 103.056
NB_HD 1
NB_HA 8
fsp3 0.38
Lipinski(0=no;1=yes) 1

FDA
NDA 062426 (pdf not found) INN (CEPHALOTHIN SODIUM) CEPHALOTHIN (INTL MEDICATION) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062435 (pdf not found) INN (CEPHALOTHIN SODIUM) SEFFIN (GLAXOSMITHKLINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062464 (pdf not found) INN (CEPHALOTHIN SODIUM) CEPHALOTHIN SODIUM (BRISTOL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062547 (pdf not found) INN (CEPHALOTHIN SODIUM) CEPHALOTHIN SODIUM (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062548 (pdf not found) INN (CEPHALOTHIN SODIUM) CEPHALOTHIN SODIUM (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062666 (pdf not found) INN (CEPHALOTHIN SODIUM) CEPHALOTHIN SODIUM (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050482 (pdf not found) INN (CEPHALOTHIN SODIUM) KEFLIN (LILLY) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 062422 (pdf not found) INN (CEPHALOTHIN SODIUM) CEPHALOTHIN SODIUM W/ SODIUM CHLORIDE IN PLASTIC CONTAINER (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 062549 (pdf not found) INN (CEPHALOTHIN SODIUM) KEFLIN IN PLASTIC CONTAINER (LILLY) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 062730 (pdf not found) INN (CEPHALOTHIN SODIUM) CEPHALOTHIN SODIUM W/ DEXTROSE IN PLASTIC CONTAINER (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1987 DISCONTINUED