e-Drug3D
1006
MITOMYCIN
INN
MITOMYCIN
cas 50-07-7
CLASS
ANTINEOPLASTIC
CROSS-LINKING REAGENTS
ALKYLATING AGENTS
INHIBITS THE SYNTHESIS OF DEOXYRIBONUCLEIC ACID (DNA)
CYTOTOXIC
ISOLATED FROM THE BROTH OF STREPTOMYCES VERTICILLUS YINGTANENSIS
ROUTE (list)
INJECTION TOPICAL PYELOCALYCEAL INTRAVESICAL
ATC code
L01DC03
PK parameters
t1/2 0.76 HOUR
TARGET DNA
Unknown
Formula:
C15H18N4O5
Calculated chemical properties:
MW 334.33
NB_atoms 24
XLogP -1.65
PSA 135.309
NB_HD 5
NB_HA 9
fsp3 0.53
Lipinski(0=no;1=yes) 1
NB_atoms 24
XLogP -1.65
PSA 135.309
NB_HD 5
NB_HA 9
fsp3 0.53
Lipinski(0=no;1=yes) 1
FDA
NDA 050450 (pdf not found) INN (MITOMYCIN) MUTAMYCIN (BRISTOL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062336 (pdf not found) INN (MITOMYCIN) MUTAMYCIN (BRISTOL MYERS) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 064106 (pdf not found) INN (MITOMYCIN) MITOMYCIN (HOSPIRA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064117 (pdf not found) INN (MITOMYCIN) MITOMYCIN (HIKMA) APPROVAL= AP YEAR= 1995
NDA 064144 (pdf not found) INN (MITOMYCIN) MITOMYCIN (ACCORD HLTHCARE) APPROVAL= AP YEAR= 1998
NDA 064180 (pdf not found) INN (MITOMYCIN) MITOMYCIN (HIKMA) APPROVAL= AP YEAR= 1999
NDA 050763 (pdf not found) INN (MITOMYCIN) MITOZYTREX (SUPERGEN) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 022572 (pdf not found) INN (MITOMYCIN) MITOSOL (GLAUKOS) APPROVAL= AP YEAR= 2012
NDA 202670 (pdf not found) INN (MITOMYCIN) MITOMYCIN (RK PHARMA) APPROVAL= AP YEAR= 2017
NDA 203386 (pdf not found) INN (MITOMYCIN) MITOMYCIN (RK PHARMA) APPROVAL= AP YEAR= 2017
NDA 211728 (pdf not found) INN (MITOMYCIN) JELMYTO (UROGEN PHARMA) APPROVAL= AP YEAR= 2020
NDA 215687 (pdf not found) INN (MITOMYCIN) MITOMYCIN (GLAND) APPROVAL= AP YEAR= 2021
NDA 214504 (pdf not found) INN (MITOMYCIN) MITOMYCIN (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 214505 (pdf not found) INN (MITOMYCIN) MITOMYCIN (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 216648 (pdf not found) INN (MITOMYCIN) MITOMYCIN (GLAND) APPROVAL= AP YEAR= 2022
NDA 216732 (pdf not found) INN (MITOMYCIN) MITOMYCIN (EUGIA PHARMA) APPROVAL= AP YEAR= 2023
NDA 211269 (pdf not found) INN (MITOMYCIN) MITOMYCIN (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2024
NDA 215793 (pdf not found) INN (MITOMYCIN) ZUSDURI (UROGEN PHARMA) APPROVAL= AP YEAR= 2025
NDA 050450 (pdf not found) INN (MITOMYCIN) MUTAMYCIN (BRISTOL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062336 (pdf not found) INN (MITOMYCIN) MUTAMYCIN (BRISTOL MYERS) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 064106 (pdf not found) INN (MITOMYCIN) MITOMYCIN (HOSPIRA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 064117 (pdf not found) INN (MITOMYCIN) MITOMYCIN (HIKMA) APPROVAL= AP YEAR= 1995
NDA 064144 (pdf not found) INN (MITOMYCIN) MITOMYCIN (ACCORD HLTHCARE) APPROVAL= AP YEAR= 1998
NDA 064180 (pdf not found) INN (MITOMYCIN) MITOMYCIN (HIKMA) APPROVAL= AP YEAR= 1999
NDA 050763 (pdf not found) INN (MITOMYCIN) MITOZYTREX (SUPERGEN) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 022572 (pdf not found) INN (MITOMYCIN) MITOSOL (GLAUKOS) APPROVAL= AP YEAR= 2012
NDA 202670 (pdf not found) INN (MITOMYCIN) MITOMYCIN (RK PHARMA) APPROVAL= AP YEAR= 2017
NDA 203386 (pdf not found) INN (MITOMYCIN) MITOMYCIN (RK PHARMA) APPROVAL= AP YEAR= 2017
NDA 211728 (pdf not found) INN (MITOMYCIN) JELMYTO (UROGEN PHARMA) APPROVAL= AP YEAR= 2020
NDA 215687 (pdf not found) INN (MITOMYCIN) MITOMYCIN (GLAND) APPROVAL= AP YEAR= 2021
NDA 214504 (pdf not found) INN (MITOMYCIN) MITOMYCIN (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 214505 (pdf not found) INN (MITOMYCIN) MITOMYCIN (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 216648 (pdf not found) INN (MITOMYCIN) MITOMYCIN (GLAND) APPROVAL= AP YEAR= 2022
NDA 216732 (pdf not found) INN (MITOMYCIN) MITOMYCIN (EUGIA PHARMA) APPROVAL= AP YEAR= 2023
NDA 211269 (pdf not found) INN (MITOMYCIN) MITOMYCIN (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2024
NDA 215793 (pdf not found) INN (MITOMYCIN) ZUSDURI (UROGEN PHARMA) APPROVAL= AP YEAR= 2025