e-Drug3D

1005

CEPHAPIRIN

DISCONTINUED

INN
CEPHAPIRIN

cas 21593-23-7

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC

ROUTE (list)

INJECTION

ATC code

J01DB08

PK parameters

VD 8.4 LITER (65 KILOGRAM)
Cl 10.5 LITER / HOUR (65 KILOGRAM)
PPB 45 PERCENT
t1/2 1.2 HOUR

Target

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

DrugCentral

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

Download SDF file

(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Formula:
C17H17N3O6S2

Calculated chemical properties:

MW 422.47
NB_atoms 28
XLogP -0.86
PSA 113.323
NB_HD 1
NB_HA 9
fsp3 0.35
Lipinski(0=no;1=yes) 1

FDA
NDA 050446 (pdf not found) INN (CEPHAPIRIN SODIUM) CEFADYL (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062723 (pdf not found) INN (CEPHAPIRIN SODIUM) CEPHAPIRIN SODIUM (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062724 (pdf not found) INN (CEPHAPIRIN SODIUM) CEFADYL (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062961 (pdf not found) INN (CEPHAPIRIN SODIUM) CEFADYL (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 061769 (pdf not found) INN (CEPHAPIRIN SODIUM) CEFADYL (APOTHECON) APPROVAL= AP YEAR= 1974 DISCONTINUED
NDA 062720 (pdf not found) INN (CEPHAPIRIN SODIUM) CEPHAPIRIN SODIUM (HIKMA) APPROVAL= AP YEAR= 1987 DISCONTINUED