e-Drug3D
100
PYRILAMINE
DISCONTINUED
INN
PYRILAMINE
cas 91-84-9
CLASS
RESPIRATORY SYSTEM
ANTIHISTAMINIC
SEDATIVES
ROUTE (list)
OPHTHALMIC ORAL
PK parameters
TARGET HISTAMINE RECEPTOR
PDB
8X63 (CRYOEM STRUCTURE OF THE HISTAMINE H1 RECEPTOR-BRIL, ANTI BRIL FAB COMPLEX WITH MEPYRAMINE)
Ligand code = Y5E (link to the list of PDB complexes)
Download experimental 3D coordinates of Y5E with added hydrogens
Histamine H1 receptor UNIPROT P35367 HRH1
Formula:
C17H23N3O
Calculated chemical properties:
MW 285.38
NB_atoms 21
XLogP 2.66
PSA 27.411
NB_HD 0
NB_HA 4
fsp3 0.35
Lipinski(0=no;1=yes) 1
NB_atoms 21
XLogP 2.66
PSA 27.411
NB_HD 0
NB_HA 4
fsp3 0.35
Lipinski(0=no;1=yes) 1
FDA
NDA 007953 (pdf not found) INN (PHENYLEPHRINE HYDROCHLORIDE ; PYRILAMINE MALEATE) PREFRIN-A (ALLERGAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080808 (pdf not found) INN (PYRILAMINE MALEATE) PYRILAMINE MALEATE (IMPAX LABS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 085231 (pdf not found) INN (PYRILAMINE MALEATE) PYRILAMINE MALEATE (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 007953 (pdf not found) INN (PHENYLEPHRINE HYDROCHLORIDE ; PYRILAMINE MALEATE) PREFRIN-A (ALLERGAN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080808 (pdf not found) INN (PYRILAMINE MALEATE) PYRILAMINE MALEATE (IMPAX LABS) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 085231 (pdf not found) INN (PYRILAMINE MALEATE) PYRILAMINE MALEATE (WATSON LABS) APPROVAL= AP YEAR= 1982 DISCONTINUED