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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NALDEMEDINE
| NALDEMEDINE | METABOLISM | ORAL | Tmax 0.75 HOUR VD 155 LITER PPB 93.5 PERCENT HT 11 HOUR SOLUBILITY SLIGHTLY SOLUBLE IN WATER | MU OPIOID RECEPTOR DELTA OPIOID RECEPTOR KAPPA OPIOID RECEPTOR | GPCR OPRM_HUMAN ANTAGONIST P35372 | EMA | |||
