e-Drug3D

992

cas 127-33-3

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
TETRACYCLINES
PRODUCT BY STREPTOMYCES AUREOFACIENS

ROUTE (list)

ORAL

PK parameters

VD 84.5 LITER (65 KILOGRAM)
Cl 4.3 LITER / HOUR (65 KILOGRAM)
PPB 65 PERCENT
t1/2 13 HOUR

MW 464.85
NB_atoms 32
XLogP 0.26
PSA 171.439
NB_HD 7
NB_HA 10
fsp3 0.38
Lipinski(0=no;1=yes) 0

FDA
NDA 050257 (pdf not found) INN (DEMECLOCYCLINE HYDROCHLORIDE) DECLOMYCIN (LEDERLE) APPROVAL= AP YEAR= 1960 DISCONTINUED
NDA 050262 (pdf not found) INN (DEMECLOCYCLINE HYDROCHLORIDE) DECLOMYCIN (LEDERLE) APPROVAL= AP YEAR= 1960 DISCONTINUED
NDA 050261 (label) INN (DEMECLOCYCLINE HYDROCHLORIDE) DECLOMYCIN (COREPHARMA) APPROVAL= AP YEAR= 1964 DISCONTINUED
NDA 065094 (pdf not found) INN (DEMECLOCYCLINE HYDROCHLORIDE) DEMECLOCYCLINE HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 065171 (pdf not found) INN (DEMECLOCYCLINE HYDROCHLORIDE) DEMECLOCYCLINE HYDROCHLORIDE (BARR) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 065425 (pdf not found) INN (DEMECLOCYCLINE HYDROCHLORIDE) DEMECLOCYCLINE HYDROCHLORIDE (AMNEAL PHARM) APPROVAL= AP YEAR= 2008
NDA 065389 (pdf not found) INN (DEMECLOCYCLINE HYDROCHLORIDE) DEMECLOCYCLINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2008
NDA 065447 (pdf not found) INN (DEMECLOCYCLINE HYDROCHLORIDE) DEMECLOCYCLINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2015