e-Drug3D

970

cas 126-07-8

CLASS

DERMATOLOGICALS
ANTIFUNGAL
ANTIBACTERIAL
ANTIBIOTICS
INDIRECT REMODELLING OF KERATIN INTERMEDIATE FILAMENTS
TUBULIN BINDING (PUTATIVE TARGET PMID22191585)

ROUTE (list)

ORAL

PK parameters

Tmax 4 HOUR
VD 45.5 LITER (65 KILOGRAM)
PPB 80 PERCENT
t1/2 16.5 HOUR

MW 352.76
NB_atoms 24
XLogP 2.81
PSA 75.311
NB_HD 0
NB_HA 6
fsp3 0.41
Lipinski(0=no;1=yes) 1

FDA
NDA 050051 (pdf not found) INN (GRISEOFULVIN MICROCRYSTALLINE) GRISACTIN (WYETH AYERST) APPROVAL= AP YEAR= 1962 DISCONTINUED
NDA 060569 (pdf not found) INN (GRISEOFULVIN MICROSIZE) FULVICIN-U/F (CHARTWELL RX) APPROVAL= AP YEAR= 1971
NDA 060618 (pdf not found) INN (GRISEOFULVIN MICROCRYSTALLINE) GRIFULVIN V (J AND J) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 050448 (pdf not found) INN (GRISEOFULVIN MICROCRYSTALLINE) GRIFULVIN V (JOHNSON AND JOHNSON) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 060212 (pdf not found) INN (GRISEOFULVIN MICROCRYSTALLINE) GRISACTIN (WYETH AYERST) APPROVAL= AP YEAR= 1972 DISCONTINUED
NDA 050475 (label) INN (GRISEOFULVIN ULTRAMICROSIZE) GRIS-PEG (BAUSCH) APPROVAL= AP YEAR= 1975
NDA 062178 (pdf not found) INN (GRISEOFULVIN ULTRAMICROCRYSTALLINE) GRISACTIN ULTRA (WYETH AYERST) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 062279 (label) INN (GRISEOFULVIN MICROSIZE) GRIFULVIN V (VALEANT LUXEMBOURG) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 061996 (pdf not found) INN (GRISEOFULVIN ULTRAMICROSIZE) FULVICIN P/G (CHARTWELL RX) APPROVAL= AP YEAR= 1982
NDA 062438 (pdf not found) INN (GRISEOFULVIN ULTRAMICROCRYSTALLINE) GRISACTIN ULTRA (WYETH AYERST) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 062483 (pdf not found) INN (GRISEOFULVIN MICROSIZE) GRIFULVIN V (VALEANT LUXEMBOURG) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 062645 (pdf not found) INN (GRISEOFULVIN ULTRAMICROCRYSTALLINE) ULTRAGRIS-165 (PLIVA) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 062646 (pdf not found) INN (GRISEOFULVIN ULTRAMICROCRYSTALLINE) ULTRAGRIS-330 (PLIVA) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 065200 (pdf not found) INN (GRISEOFULVIN MICROSIZE) GRISEOFULVIN (CHARTWELL RX) APPROVAL= AP YEAR= 2005
NDA 065354 (pdf not found) INN (GRISEOFULVIN MICROSIZE) GRISEOFULVIN (CIPLA) APPROVAL= AP YEAR= 2007
NDA 065394 (pdf not found) INN (GRISEOFULVIN MICROSIZE) GRISEOFULVIN (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 2007
NDA 065438 (pdf not found) INN (GRISEOFULVIN MICROSIZE) GRISEOFULVIN (COSETTE PHARMS NC) APPROVAL= AP YEAR= 2010
NDA 202482 (pdf not found) INN (GRISEOFULVIN MICROSIZE) GRISEOFULVIN (SIGMAPHARM LABS LLC) APPROVAL= AP YEAR= 2012
NDA 202545 (pdf not found) INN (GRISEOFULVIN ULTRAMICROSIZE) GRISEOFULVIN,ULTRAMICROSIZE (SIGMAPHARM LABS LLC) APPROVAL= AP YEAR= 2012
NDA 091592 (pdf not found) INN (GRISEOFULVIN MICROSIZE) GRISEOFULVIN (SANDOZ) APPROVAL= AP YEAR= 2013
NDA 204371 (pdf not found) INN (GRISEOFULVIN ULTRAMICROSIZE) GRISEOFULVIN, ULTRAMICROSIZE (MOUNTAIN) APPROVAL= AP YEAR= 2014
NDA 202805 (pdf not found) INN (GRISEOFULVIN ULTRAMICROSIZE) GRISEOFULVIN, ULTRAMICROSIZE (SANDOZ) APPROVAL= AP YEAR= 2018