e-Drug3D
967
DICLOXACILLIN
INN
DICLOXACILLIN
cas 3116-76-5
CLASS
ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
ROUTE (list)
ORAL
ATC code
J01CF01
PK parameters
VD 7.1 LITER (65 KILOGRAM)
Cl 7.8 LITER / HOUR (65 KILOGRAM)
PPB 96 PERCENT
t1/2 0.88 HOUR
TARGET PENICILLIN-BINDING PROTEINS 1A/1B
Penicillin-binding protein UNIPROT P72355 pbp4
Formula:
C19H17Cl2N3O5S
Calculated chemical properties:
MW 469.32
NB_atoms 30
XLogP 1.87
PSA 107.743
NB_HD 1
NB_HA 8
fsp3 0.37
Lipinski(0=no;1=yes) 1
NB_atoms 30
XLogP 1.87
PSA 107.743
NB_HD 1
NB_HA 8
fsp3 0.37
Lipinski(0=no;1=yes) 1
FDA
NDA 050337 (pdf not found) INN (DICLOXACILLIN SODIUM) DYNAPEN (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060254 (pdf not found) INN (DICLOXACILLIN SODIUM) DYCILL (GLAXOSMITHKLINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050011 (pdf not found) INN (DICLOXACILLIN SODIUM) PATHOCIL (WYETH AYERST) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 050092 (pdf not found) INN (DICLOXACILLIN SODIUM) PATHOCIL (WYETH AYERST) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 061454 (pdf not found) INN (DICLOXACILLIN SODIUM) DICLOXACILLIN SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 061455 (pdf not found) INN (DICLOXACILLIN SODIUM) DICLOXACILLIN SODIUM (APOTHECON) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 062238 (pdf not found) INN (DICLOXACILLIN SODIUM) DYCILL (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 062286 (pdf not found) INN (DICLOXACILLIN SODIUM) DICLOXACILLIN SODIUM (TEVA) APPROVAL= AP YEAR= 1982
NDA 216845 (pdf not found) INN (DICLOXACILLIN SODIUM) DICLOXACILLIN SODIUM (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2022
NDA 050337 (pdf not found) INN (DICLOXACILLIN SODIUM) DYNAPEN (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 060254 (pdf not found) INN (DICLOXACILLIN SODIUM) DYCILL (GLAXOSMITHKLINE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050011 (pdf not found) INN (DICLOXACILLIN SODIUM) PATHOCIL (WYETH AYERST) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 050092 (pdf not found) INN (DICLOXACILLIN SODIUM) PATHOCIL (WYETH AYERST) APPROVAL= AP YEAR= 1968 DISCONTINUED
NDA 061454 (pdf not found) INN (DICLOXACILLIN SODIUM) DICLOXACILLIN SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 061455 (pdf not found) INN (DICLOXACILLIN SODIUM) DICLOXACILLIN SODIUM (APOTHECON) APPROVAL= AP YEAR= 1971 DISCONTINUED
NDA 062238 (pdf not found) INN (DICLOXACILLIN SODIUM) DYCILL (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 062286 (pdf not found) INN (DICLOXACILLIN SODIUM) DICLOXACILLIN SODIUM (TEVA) APPROVAL= AP YEAR= 1982
NDA 216845 (pdf not found) INN (DICLOXACILLIN SODIUM) DICLOXACILLIN SODIUM (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2022