e-Drug3D
944
LUBIPROSTONE
INN
LUBIPROSTONE
cas 333963-40-9
CLASS
METABOLISM
ANTI-CONSTIPATION AGENTS
LAXATIVES
ROUTE (list)
ORAL
ATC code
A06AX03
PK parameters
PPB 94 PERCENT
Solubility
PRACTICALLY INSOLUBLE IN WATER
TARGET CHLORIDE CHANNEL PROTEIN 2 (CLC-2)
Chloride channel protein 2 UNIPROT P51788 CLCN2
Formula:
C20H32F2O5
Calculated chemical properties:
MW 389.45
NB_atoms 27
XLogP 2.98
PSA 79.19
NB_HD 1
NB_HA 5
fsp3 0.90
Lipinski(0=no;1=yes) 1
NB_atoms 27
XLogP 2.98
PSA 79.19
NB_HD 1
NB_HA 5
fsp3 0.90
Lipinski(0=no;1=yes) 1
FDA
NDA 021908 (label) INN (LUBIPROSTONE) AMITIZA (SUCAMPO PHARMA LLC) APPROVAL= AP YEAR= 2006 NEWMOLECULARENTITY
NDA 209450 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (AMNEAL) APPROVAL= AP YEAR= 2021
NDA 201442 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (PH HEALTH) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 206994 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (DR REDDYS) APPROVAL= AP YEAR= 2022
NDA 209920 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2022
NDA 214131 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2023
NDA 218640 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (ASCENT PHARMS INC) APPROVAL= AP YEAR= 2025
NDA 021908 (label) INN (LUBIPROSTONE) AMITIZA (SUCAMPO PHARMA LLC) APPROVAL= AP YEAR= 2006 NEWMOLECULARENTITY
NDA 209450 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (AMNEAL) APPROVAL= AP YEAR= 2021
NDA 201442 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (PH HEALTH) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 206994 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (DR REDDYS) APPROVAL= AP YEAR= 2022
NDA 209920 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2022
NDA 214131 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2023
NDA 218640 (pdf not found) INN (LUBIPROSTONE) LUBIPROSTONE (ASCENT PHARMS INC) APPROVAL= AP YEAR= 2025