e-Drug3D
912
MICAFUNGIN
INN
MICAFUNGIN
cas 235114-32-6
CLASS
ANTIINFECTIVES
ANTIFUNGALS
MEMBER OF THE ECHINOCANDIN CLASS OF ANTIFUNGAL AGENTS
ROUTE (list)
INTRAVENOUS INJECTION
ATC code
J02AX05
PK parameters
Cmax 7.95 MICROMOLAR
VD 25.35 LITER (65 KILOGRAM)
Cl 1.16 LITER / HOUR (65 KILOGRAM)
PPB 99 PERCENT
t1/2 13.4 HOUR
Solubility
FREELY SOLUBLE IN WATER
TARGET BETA-1,3-GLUCAN SYNTHASE
Beta-1,3-glucan synthase catalytic subunit 1 UNIPROT O13428 GSC1
Formula:
C56H71N9O23S
Calculated chemical properties:
MW 1270.29
NB_atoms 89
XLogP -3.90
PSA 452.725
NB_HD 17
NB_HA 32
fsp3 0.48
Lipinski(0=no;1=yes) 0
NB_atoms 89
XLogP -3.90
PSA 452.725
NB_HD 17
NB_HA 32
fsp3 0.48
Lipinski(0=no;1=yes) 0
FDA
NDA 021506 (label) INN (MICAFUNGIN SODIUM) MYCAMINE (ASTELLAS) APPROVAL= TA YEAR= 2005
NDA 021754 (label) INN (MICAFUNGIN SODIUM) MYCAMINE (FUJISAWA HLTHCARE) APPROVAL= AP YEAR= 2005 NEWAPPLICATION
NDA 207344 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2019
NDA 208366 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (APOTEX) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 212125 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213363 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (JIANGSU HANSOH PHARM) APPROVAL= AP YEAR= 2021
NDA 211713 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (XELLIA PHARMS APS) APPROVAL= AP YEAR= 2021
NDA 212156 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN (PH HEALTH) APPROVAL= AP YEAR= 2021
NDA 213261 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (HIKMA) APPROVAL= AP YEAR= 2021
NDA 215241 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (ZYDUS PHARMS) APPROVAL= AP YEAR= 2022
NDA 215381 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 216142 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN IN SODIUM CHLORIDE 0.9% (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2023
NDA 216438 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (BIOCON PHARMA) APPROVAL= AP YEAR= 2024
NDA 219273 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (QILU PHARM HAINAN) APPROVAL= AP YEAR= 2025
NDA 219518 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2026
NDA 219712 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (HISUN PHARM HANGZHOU) APPROVAL= AP YEAR= 2026
NDA 220296 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (ASPIRO) APPROVAL= AP YEAR= 2026
NDA 021506 (label) INN (MICAFUNGIN SODIUM) MYCAMINE (ASTELLAS) APPROVAL= TA YEAR= 2005
NDA 021754 (label) INN (MICAFUNGIN SODIUM) MYCAMINE (FUJISAWA HLTHCARE) APPROVAL= AP YEAR= 2005 NEWAPPLICATION
NDA 207344 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2019
NDA 208366 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (APOTEX) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 212125 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2021 DISCONTINUED
NDA 213363 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (JIANGSU HANSOH PHARM) APPROVAL= AP YEAR= 2021
NDA 211713 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (XELLIA PHARMS APS) APPROVAL= AP YEAR= 2021
NDA 212156 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN (PH HEALTH) APPROVAL= AP YEAR= 2021
NDA 213261 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (HIKMA) APPROVAL= AP YEAR= 2021
NDA 215241 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (ZYDUS PHARMS) APPROVAL= AP YEAR= 2022
NDA 215381 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (MEITHEAL) APPROVAL= AP YEAR= 2022
NDA 216142 (label) INN (MICAFUNGIN SODIUM) MICAFUNGIN IN SODIUM CHLORIDE 0.9% (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2023
NDA 216438 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (BIOCON PHARMA) APPROVAL= AP YEAR= 2024
NDA 219273 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (QILU PHARM HAINAN) APPROVAL= AP YEAR= 2025
NDA 219518 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (YICHANG HUMANWELL) APPROVAL= AP YEAR= 2026
NDA 219712 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (HISUN PHARM HANGZHOU) APPROVAL= AP YEAR= 2026
NDA 220296 (pdf not found) INN (MICAFUNGIN SODIUM) MICAFUNGIN SODIUM (ASPIRO) APPROVAL= AP YEAR= 2026