e-Drug3D
830
AMINOLEVULINIC ACID
INN
AMINOLEVULINIC ACID
cas 106-60-5
CLASS
ANTINEOPLASTIC
DERMATOLOGIC
CHEMOPHOTODYNAMIC
PHOTOSENSITIZING AGENTS
A PORPHYRIN PRECURSOR
TREATMENT OF MINIMALLY TO MODERATELY THICK ACTINIC KERATOSES OF THE FACE OR SCALP
MALIGNANT GLIOMA (DRUG FOR RARE DISEASE IN EUROPE)
ROUTE (list)
TOPICAL ORAL
ATC code
L01XD04
PK parameters
F 55 PERCENT
t1/2 0.7 HOUR
Solubility
VERY SOLUBLE IN WATER
-
PDB
6HZP (CRYSTAL STRUCTURE OF A POT FAMILY TRANSPORTER IN COMPLEX WITH 5-AMINOLEVULINIC ACID)
Ligand code = FVT (link to the list of PDB complexes)
Download experimental 3D coordinates of FVT with added hydrogens
Unknown
Formula:
C5H9NO3
Calculated chemical properties:
MW 130.12
NB_atoms 9
XLogP -1.96
PSA 76.587
NB_HD 2
NB_HA 4
fsp3 0.60
Lipinski(0=no;1=yes) 1
NB_atoms 9
XLogP -1.96
PSA 76.587
NB_HD 2
NB_HA 4
fsp3 0.60
Lipinski(0=no;1=yes) 1
FDA
NDA 020965 (label) INN (AMINOLEVULINIC ACID HYDROCHLORIDE) LEVULAN (SUN PHARM INDS INC) APPROVAL= AP YEAR= 1999 NEWMOLECULARENTITY
NDA 208081 (label) INN (AMINOLEVULINIC ACID HYDROCHLORIDE) AMELUZ (BIOFRONTERA) APPROVAL= AP YEAR= 2016
NDA 208630 (label) INN (AMINOLEVULINIC ACID HYDROCHLORIDE) GLEOLAN (NXDC) APPROVAL= AP YEAR= 2017
NDA 020965 (label) INN (AMINOLEVULINIC ACID HYDROCHLORIDE) LEVULAN (SUN PHARM INDS INC) APPROVAL= AP YEAR= 1999 NEWMOLECULARENTITY
NDA 208081 (label) INN (AMINOLEVULINIC ACID HYDROCHLORIDE) AMELUZ (BIOFRONTERA) APPROVAL= AP YEAR= 2016
NDA 208630 (label) INN (AMINOLEVULINIC ACID HYDROCHLORIDE) GLEOLAN (NXDC) APPROVAL= AP YEAR= 2017