e-Drug3D

814

cas 144701-48-4

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANGIOTENSIN II RECEPTOR ANTAGONIST

ROUTE (list)

ORAL

PK parameters

F 58 PERCENT
Tmax 0.75 HOUR
VD 500 LITER
Cl 48 LITER / HOUR
PPB 99.5 PERCENT
t1/2 24 HOUR

TARGET ANGIOTENSIN II RECEPTOR

PDB
3VN2 (CRYSTAL STRUCTURE OF PPARGAMMA COMPLEXED WITH TELMISARTAN)

Ligand code = TLS (link to the list of PDB complexes)

Download experimental 3D coordinates of TLS with added hydrogens

MW 513.60
NB_atoms 39
XLogP 5.93
PSA 61.323
NB_HD 0
NB_HA 6
fsp3 0.18
Lipinski(0=no;1=yes) 0

FDA
NDA 020850 (label) INN (TELMISARTAN) MICARDIS (BOEHRINGER INGELHEIM) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 021162 (label) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) MICARDIS HCT (BOEHRINGER INGELHEIM) APPROVAL= AP YEAR= 2000
NDA 022401 (label) INN (AMLODIPINE BESYLATE ; TELMISARTAN) TWYNSTA (BOEHRINGER INGELHEIM) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 091084 (pdf not found) INN (TELMISARTAN ; HYDROCHLOROTHIAZIDE) TELMISARTAN; HYDROCHLOROTHIAZIDE (WATSON LABS FLORIDA) APPROVAL= TA YEAR= 2011
NDA 078710 (pdf not found) INN (TELMISARTAN) TELMISARTAN (CHARTWELL RX) APPROVAL= AP YEAR= 2014
NDA 091351 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) TELMISARTAN AND HYDROCHLOROTHIAZIDE (LUPIN) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 090032 (pdf not found) INN (TELMISARTAN) TELMISARTAN (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2014
NDA 201586 (pdf not found) INN (AMLODIPINE BESYLATE ; TELMISARTAN) TELMISARTAN AND AMLODIPINE (LUPIN) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202130 (pdf not found) INN (TELMISARTAN) TELMISARTAN (ALEMBIC) APPROVAL= AP YEAR= 2014
NDA 091648 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) TELMISARTAN AND HYDROCHLOROTHIAZIDE (NATCO) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 201192 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) TELMISARTAN AND HYDROCHLOROTHIAZIDE (TORRENT) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202397 (pdf not found) INN (TELMISARTAN) TELMISARTAN (MYLAN) APPROVAL= AP YEAR= 2014
NDA 202516 (pdf not found) INN (AMLODIPINE BESYLATE ; TELMISARTAN) TELMISARTAN AND AMLODIPINE (MYLAN) APPROVAL= AP YEAR= 2014
NDA 202517 (pdf not found) INN (AMLODIPINE BESYLATE ; TELMISARTAN) TELMISARTAN AND AMLODIPINE (TORRENT) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 203010 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) TELMISARTAN AND HYDROCHLOROTHIAZIDE (ALEMBIC) APPROVAL= AP YEAR= 2014
NDA 203171 (pdf not found) INN (TELMISARTAN) TELMISARTAN (TORRENT) APPROVAL= AP YEAR= 2014
NDA 203325 (pdf not found) INN (TELMISARTAN) TELMISARTAN (ZYDUS PHARMS) APPROVAL= AP YEAR= 2014
NDA 203867 (pdf not found) INN (TELMISARTAN) TELMISARTAN (SANDOZ) APPROVAL= AP YEAR= 2014
NDA 204169 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) TELMISARTAN AND HYDROCHLOROTHIAZIDE (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 204415 (pdf not found) INN (TELMISARTAN) TELMISARTAN (AMNEAL PHARMS) APPROVAL= AP YEAR= 2015
NDA 205150 (pdf not found) INN (TELMISARTAN) TELMISARTAN (INVENTIA) APPROVAL= AP YEAR= 2015
NDA 206511 (pdf not found) INN (TELMISARTAN) TELMISARTAN (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2015
NDA 205901 (label) INN (TELMISARTAN) TELMISARTAN (HETERO LABS LTD V) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 204164 (pdf not found) INN (TELMISARTAN) TELMISARTAN (JUBILANT GENERICS) APPROVAL= AP YEAR= 2016
NDA 205234 (pdf not found) INN (AMLODIPINE BESYLATE ; TELMISARTAN) TELMISARTAN AND AMLODIPINE (ALEMBIC) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 208727 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) TELMISARTAN AND HYDROCHLOROTHIAZIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2016
NDA 207882 (pdf not found) INN (TELMISARTAN) TELMISARTAN (PRINSTON INC) APPROVAL= AP YEAR= 2017
NDA 208605 (pdf not found) INN (TELMISARTAN) TELMISARTAN (CADILA PHARMS LTD) APPROVAL= AP YEAR= 2017
NDA 204221 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) TELMISARTAN AND HYDROCHLOROTHIAZIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2017
NDA 207016 (pdf not found) INN (TELMISARTAN) TELMISARTAN (MICRO LABS) APPROVAL= AP YEAR= 2017
NDA 209028 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) TELMISARTAN AND HYDROCHLOROTHIAZIDE (PRINSTON INC) APPROVAL= AP YEAR= 2017
NDA 202544 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) TELMISARTAN AND HYDROCHLOROTHIAZIDE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2019
NDA 207843 (pdf not found) INN (TELMISARTAN) TELMISARTAN (HISUN PHARM HANGZHOU) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 218157 (pdf not found) INN (TELMISARTAN) TELMISARTAN (MANKIND PHARMA) APPROVAL= AP YEAR= 2024
NDA 203986 (pdf not found) INN (TELMISARTAN) TELMISARTAN (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2025
NDA 218406 (pdf not found) INN (HYDROCHLOROTHIAZIDE ; TELMISARTAN) TELMISARTAN AND HYDROCHLOROTHIAZIDE (MANKIND PHARMA) APPROVAL= AP YEAR= 2025 DISCONTINUED
NDA 219423 (label) INN (AMLODIPINE BESYLATE ; INDAPAMIDE ; TELMISARTAN) WIDAPLIK (AZURITY) APPROVAL= AP YEAR= 2025 DISCONTINUED