e-Drug3D

802

cas 68291-97-4

CLASS

NERVOUS SYSTEM
ANTICONVULSANT
CARBONIC ANHYDRASE INHIBITOR

ROUTE (list)

ORAL

PK parameters

Tmax 4 HOUR
VD 94 LITER (65 KILOGRAM)
Cl 1.17 LITER / HOUR (65 KILOGRAM)
PPB 40 PERCENT
t1/2 63 HOUR

TARGET SODIUM CHANNEL
VOLTAGE-DEPENDENT CALCIUM CHANNEL
GABA/BENZODIAZEPINE RECEPTOR IONOPHORE COMPLEX
CARBONIC ANHYDRASE

PDB
3PO7 (HUMAN MONOAMINE OXIDASE B IN COMPLEX WITH ZONISAMIDE)

Ligand code = ZON (link to the list of PDB complexes)

Download experimental 3D coordinates of ZON with added hydrogens

MW 212.23
NB_atoms 14
XLogP 0.62
PSA 86.32
NB_HD 2
NB_HA 5
fsp3 0.12
Lipinski(0=no;1=yes) 1

FDA
NDA 020789 (label) INN (ZONISAMIDE) ZONEGRAN (ADVANZ PHARMA) APPROVAL= AP YEAR= 2000
NDA 077635 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077636 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (GRANULES) APPROVAL= AP YEAR= 2005
NDA 077637 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (RISING) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077639 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (ANI PHARMS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077641 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (ANI PHARMS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077642 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (APOTEX) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077644 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077645 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2005
NDA 077647 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077648 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (ROXANE) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077625 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2006
NDA 077634 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (SUN PHARM INDS (IN)) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077650 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077651 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (GLENMARK PHARMS) APPROVAL= AP YEAR= 2006
NDA 077813 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (BIONPHARMA) APPROVAL= AP YEAR= 2006
NDA 077869 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2006
NDA 077891 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (DR REDDYS LABS LTD) APPROVAL= AP YEAR= 2006 OBSOLETE
NDA 077876 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 214492 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (UNICHEM) APPROVAL= AP YEAR= 2021
NDA 214273 (label) INN (ZONISAMIDE) ZONISADE (AZURITY) APPROVAL= AP YEAR= 2022
NDA 219507 (pdf not found) INN (ZONISAMIDE) ZONISAMIDE (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2025 DISCONTINUED