e-Drug3D

MECHLORETHAMINE

INN
MECHLORETHAMINE

cas 51-75-2

CLASS

ANTINEOPLASTIC
ALKYLATING AGENTS
TREATMENT OF HODGKIN'S DISEASE
UNDERGOES RAPID CHEMICAL TRANSFORMATION
THE DRUG IS NO LONGER PRESENT IN ACTIVE FORM A FEW MINUTES AFTER ADMINISTRATION

ROUTE (list)

INJECTION TOPICAL

ATC code

L01AA05

PK parameters

Solubility

VERY SOLUBLE IN WATER

Target

TARGET DNA

DrugCentral

Unknown

Download SDF file

2-chloro-N-(2-chloroethyl)-N-methylethanamine

Formula:
C5H11Cl2N

Calculated chemical properties:

MW 156.05
NB_atoms 8
XLogP 1.40
PSA 5.671
NB_HD 0
NB_HA 1
fsp3 1.00
Lipinski(0=no;1=yes) 1

FDA
NDA 006695 (label) INN (MECHLORETHAMINE HYDROCHLORIDE) MUSTARGEN (RECORDATI RARE) APPROVAL= AP YEAR= 1949 DISCONTINUED
NDA 202317 (label) INN (MECHLORETHAMINE HYDROCHLORIDE) VALCHLOR (HELSINN) APPROVAL= AP YEAR= 2013