e-Drug3D
7
GUANIDINE
DISCONTINUED
INN
GUANIDINE
cas 113-00-8
CLASS
CARDIOVASCULAR
PARASYMPATHOMIMETICS
ANTIHYPERTENSIVE
FOUND IN URINE AS A NORMAL PRODUCT OF PROTEIN METABOLISM
ROUTE (list)
ORAL
ATC code
PK parameters
Solubility
VERY SOLUBLE IN WATER
-
PDB
1O04 (CYS302SER MUTANT OF HUMAN MITOCHONDRIAL ALDEHYDE DEHYDROGENASE COMPLEXED WITH NAD+ AND MG2+)
Ligand code = GAI (link to the list of PDB complexes)
Download experimental 3D coordinates of GAI with added hydrogens
Voltage-gated potassium channel UNIPROT O43525 KCNQ3
Formula:
CH5N3
Calculated chemical properties:
MW 60.09
NB_atoms 4
XLogP -2.98
PSA 73.021
NB_HD 6
NB_HA 2
fsp3 0.00
Lipinski(0=no;1=yes) 0
NB_atoms 4
XLogP -2.98
PSA 73.021
NB_HD 6
NB_HA 2
fsp3 0.00
Lipinski(0=no;1=yes) 0
FDA
NDA 001546 (pdf not found) INN (GUANIDINE HYDROCHLORIDE) GUANIDINE HYDROCHLORIDE (MERCK SHARP DOHME) APPROVAL= AP YEAR= 1939 DISCONTINUED
NDA 001546 (pdf not found) INN (GUANIDINE HYDROCHLORIDE) GUANIDINE HYDROCHLORIDE (MERCK SHARP DOHME) APPROVAL= AP YEAR= 1939 DISCONTINUED