e-Drug3D

694

cas 91161-71-6

CLASS

DERMATOLOGICALS
ANTIFUNGAL
ALLYLAMINES
INHIBITS BIOSYNTHESIS OF ERGOSTEROL

ROUTE (list)

TOPICAL ORAL

PK parameters

F 70 PERCENT
Tmax 2 HOUR
Cl 27 LITER / HOUR
PPB 99 PERCENT
t1/2 21 HOUR

MW 291.42
NB_atoms 22
XLogP 4.88
PSA 5.171
NB_HD 0
NB_HA 1
fsp3 0.33
Lipinski(0=no;1=yes) 1

FDA
NDA 020192 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) LAMISIL (NOVARTIS) APPROVAL= AP YEAR= 1992 NEWMOLECULARENTITY DISCONTINUED
NDA 020539 (label) INN (TERBINAFINE HYDROCHLORIDE) LAMISIL (NOVARTIS) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 020749 (label) INN (TERBINAFINE HYDROCHLORIDE) LAMISIL (KARO HLTHCARE) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 020846 (label) INN (TERBINAFINE) LAMISIL (KARO HLTHCARE) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 020980 (label) INN (TERBINAFINE HYDROCHLORIDE) LAMISIL (KARO HLTHCARE) APPROVAL= AP YEAR= 1999
NDA 021124 (label) INN (TERBINAFINE HYDROCHLORIDE) LAMISIL AT (KARO HLTHCARE) APPROVAL= AP YEAR= 2000
NDA 076713 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (ANDRX PHARM) APPROVAL= TA YEAR= 2004
NDA 077065 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (GEDEON RICHTER USA) APPROVAL= TA YEAR= 2005
NDA 077136 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (MYLAN) APPROVAL= TA YEAR= 2005
NDA 077223 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (ROXANE) APPROVAL= TA YEAR= 2005
NDA 077444 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (RANBAXY) APPROVAL= TA YEAR= 2005 OBSOLETE
NDA 021958 (label) INN (TERBINAFINE) LAMISIL AT (KARO HLTHCARE) APPROVAL= AP YEAR= 2006
NDA 022071 (label) INN (TERBINAFINE HYDROCHLORIDE) LAMISIL (NOVARTIS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 076377 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (HERITAGE PHARMA AVET) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 076390 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (SENORES PHARMS) APPROVAL= AP YEAR= 2007
NDA 077137 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (CIPLA) APPROVAL= AP YEAR= 2007
NDA 077195 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (NATCO PHARMA) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077511 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (SUN PHARMA CANADA) APPROVAL= AP YEAR= 2007
NDA 077533 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077919 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (EMED MEDCL) APPROVAL= AP YEAR= 2007
NDA 078157 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2007
NDA 078163 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (ORBION PHARMS) APPROVAL= AP YEAR= 2007
NDA 078199 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (CHARTWELL) APPROVAL= AP YEAR= 2007
NDA 078229 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (WOCKHARDT) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078297 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2007
NDA 077714 (pdf not found) INN (TERBINAFINE HYDROCHLORIDE) TERBINAFINE HYDROCHLORIDE (BRECKENRIDGE PHARM) APPROVAL= AP YEAR= 2010 DISCONTINUED