e-Drug3D

670

TYLOXAPOL

DISCONTINUED

INN
TYLOXAPOL

cas 140-66-9

CLASS

RESPIRATORY SYSTEM
DETERGENTS
SURFACE-ACTIVE AGENTS
EXPECTORANT
PREVENTS THE CATABOLISM OF TRIGLYCERIDES-RICH LIPOPROTEINS BY SERUM LIPASES AND ALLOWS A TIME-DEPENDENT AND LINEAR INCREASE IN PLASMA TRIGLYCERIDES LEVELS

ROUTE (list)

INTRATRACHEAL

ATC code

R05CA01

PK parameters

Target

PDB
4MGA (CRYSTAL STRUCTURE OF HERA-LBD (Y537S) IN COMPLEX WITH 4-TERT-OCTYLPHENOL)

Ligand code = 27L (link to the list of PDB complexes)

Download experimental 3D coordinates of 27L with added hydrogens

DrugCentral

Unknown

Download SDF file

N-(furan-2-ylmethyl)-2-[methyl-[2-(phenoxy)acetyl]amino]benzamide

Formula:
C14H22O

Calculated chemical properties:

MW 206.32
NB_atoms 15
XLogP 4.11
PSA 21.36
NB_HD 1
NB_HA 1
fsp3 0.57
Lipinski(0=no;1=yes) 1

FDA
NDA 020044 (pdf not found) INN (CETYL ALCOHOL ; COLFOSCERIL PALMITATE ; TYLOXAPOL) EXOSURF NEONATAL (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1990 DISCONTINUED