e-Drug3D
659
FLUTICASONE PROPIONATE
INN
FLUTICASONE PROPIONATE
cas 80474-14-2
CLASS
DERMATOLOGICALS
ANTI-ALLERGIC AGENTS
ANTI-INFLAMMATORY AGENTS
CORTICOIDS
ANTIPRURITIC
VASOCONSTRICTIVE PROPERTIES
ROUTE (list)
TOPICAL NASAL INHALATION
ATC code
D07AC17
R01AD08
R03BA05
R01AD12
R03BA09
R01AD58
R03AK11
R03AK06
R03AK10
R03AL08
PK parameters
VD 273 LITER (65 KILOGRAM)
Cl 65.5 LITER / HOUR
PPB 91 PERCENT
t1/2 10 HOUR
Solubility
INSOLUBLE IN WATER
TARGET GLUCOCORTICOID RECEPTOR
Glucocorticoid receptor UNIPROT P04150 NR3C1
Formula:
C25H31F3O5S
Calculated chemical properties:
MW 500.57
NB_atoms 34
XLogP 4.43
PSA 63.983
NB_HD 1
NB_HA 5
fsp3 0.72
Lipinski(0=no;1=yes) 0
NB_atoms 34
XLogP 4.43
PSA 63.983
NB_HD 1
NB_HA 5
fsp3 0.72
Lipinski(0=no;1=yes) 0
FDA
NDA 019957 (label) INN (FLUTICASONE PROPIONATE) CUTIVATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 1990 NEWMOLECULARENTITY DISCONTINUED
NDA 019958 (label) INN (FLUTICASONE PROPIONATE) CUTIVATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 020121 (label) INN (FLUTICASONE PROPIONATE) FLONASE (HALEON US HOLDINGS) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 020548 (label) INN (FLUTICASONE PROPIONATE) FLOVENT (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 020549 (label) INN (FLUTICASONE PROPIONATE) FLOVENT (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 020833 (label) INN (FLUTICASONE PROPIONATE) FLOVENT DISKUS 50 (GLAXO GRP LTD) APPROVAL= AP YEAR= 2000
NDA 021077 (label) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) ADVAIR DISKUS 100/50 (GLAXO GRP LTD) APPROVAL= AP YEAR= 2000
NDA 021433 (label) INN (FLUTICASONE PROPIONATE) FLOVENT HFA (GLAXO GRP LTD) APPROVAL= AP YEAR= 2004
NDA 076300 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (CHARTWELL RX) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076451 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2004
NDA 076633 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (ENCUBE) APPROVAL= AP YEAR= 2004
NDA 076668 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2004
NDA 076793 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2004
NDA 076865 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (NESHER PHARMS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 021152 (label) INN (FLUTICASONE PROPIONATE) CUTIVATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077145 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (TARO PHARM INDS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 021254 (label) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) ADVAIR HFA (GLAXO GRP LTD) APPROVAL= AP YEAR= 2006
NDA 076504 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (HIKMA) APPROVAL= AP YEAR= 2006
NDA 077055 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (COSETTE PHARMS NC) APPROVAL= AP YEAR= 2006
NDA 077168 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (COSETTE PHARMS NC) APPROVAL= AP YEAR= 2006
NDA 077538 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (APOTEX) APPROVAL= AP YEAR= 2007
NDA 077570 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (HIKMA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 090759 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 078492 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (CHARTWELL RX) APPROVAL= AP YEAR= 2012
NDA 202236 (label) INN (AZELASTINE HYDROCHLORIDE ; FLUTICASONE PROPIONATE) DYMISTA (MYLAN SPECIALITY LP) APPROVAL= AP YEAR= 2012
NDA 091553 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2013
NDA 205434 (label) INN (FLUTICASONE PROPIONATE) FLONASE ALLERGY RELIEF (HALEON US HOLDINGS) APPROVAL= AP YEAR= 2014
NDA 207957 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (HIKMA) APPROVAL= AP YEAR= 2016
NDA 208150 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (APOTEX) APPROVAL= AP YEAR= 2016
NDA 207712 (pdf not found) INN (AZELASTINE HYDROCHLORIDE ; FLUTICASONE PROPIONATE) AZELASTINE HYDROCHLORIDE AND FLUTICASONE PROPIONATE (APOTEX) APPROVAL= AP YEAR= 2017
NDA 208798 (label) INN (FLUTICASONE PROPIONATE) ARMONAIR RESPICLICK (TEVA PHARM) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 208799 (label) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) AIRDUO RESPICLICK (TEVA PHARM) APPROVAL= AP YEAR= 2017
NDA 209022 (label) INN (FLUTICASONE PROPIONATE) XHANCE (PARATEK PHARMS) APPROVAL= AP YEAR= 2017
NDA 208024 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (HIKMA) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 208891 (label) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) WIXELA INHUB (MYLAN) APPROVAL= AP YEAR= 2019
NDA 203433 (pdf not found) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE (HIKMA) APPROVAL= AP YEAR= 2020
NDA 208111 (pdf not found) INN (AZELASTINE HYDROCHLORIDE ; FLUTICASONE PROPIONATE) AZELASTINE HYDROCHLORIDE AND FLUTICASONE PROPIONATE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2021
NDA 213948 (pdf not found) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2021
NDA 215343 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (BRIGHT) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 217088 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2024
NDA 208436 (pdf not found) INN (AZELASTINE HYDROCHLORIDE ; FLUTICASONE PROPIONATE) AZELASTINE HYDROCHLORIDE AND FLUTICASONE PROPIONATE (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2025
NDA 218321 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (RUBICON RESEARCH) APPROVAL= AP YEAR= 2025
NDA 219060 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (RUBICON RESEARCH) APPROVAL= AP YEAR= 2025
NDA 214464 (pdf not found) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE (RESPIRENT PHARMS) APPROVAL= AP YEAR= 2026
NDA 218742 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (GLENMARK SPECLT) APPROVAL= AP YEAR= 2026
NDA 219602 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (GLENMARK SPECLT) APPROVAL= AP YEAR= 2026
NDA 019957 (label) INN (FLUTICASONE PROPIONATE) CUTIVATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 1990 NEWMOLECULARENTITY DISCONTINUED
NDA 019958 (label) INN (FLUTICASONE PROPIONATE) CUTIVATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 1990 DISCONTINUED
NDA 020121 (label) INN (FLUTICASONE PROPIONATE) FLONASE (HALEON US HOLDINGS) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 020548 (label) INN (FLUTICASONE PROPIONATE) FLOVENT (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 020549 (label) INN (FLUTICASONE PROPIONATE) FLOVENT (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 020833 (label) INN (FLUTICASONE PROPIONATE) FLOVENT DISKUS 50 (GLAXO GRP LTD) APPROVAL= AP YEAR= 2000
NDA 021077 (label) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) ADVAIR DISKUS 100/50 (GLAXO GRP LTD) APPROVAL= AP YEAR= 2000
NDA 021433 (label) INN (FLUTICASONE PROPIONATE) FLOVENT HFA (GLAXO GRP LTD) APPROVAL= AP YEAR= 2004
NDA 076300 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (CHARTWELL RX) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076451 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2004
NDA 076633 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (ENCUBE) APPROVAL= AP YEAR= 2004
NDA 076668 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2004
NDA 076793 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2004
NDA 076865 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (NESHER PHARMS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 021152 (label) INN (FLUTICASONE PROPIONATE) CUTIVATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077145 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (TARO PHARM INDS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 021254 (label) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) ADVAIR HFA (GLAXO GRP LTD) APPROVAL= AP YEAR= 2006
NDA 076504 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (HIKMA) APPROVAL= AP YEAR= 2006
NDA 077055 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (COSETTE PHARMS NC) APPROVAL= AP YEAR= 2006
NDA 077168 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (COSETTE PHARMS NC) APPROVAL= AP YEAR= 2006
NDA 077538 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (APOTEX) APPROVAL= AP YEAR= 2007
NDA 077570 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (HIKMA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 090759 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 078492 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (CHARTWELL RX) APPROVAL= AP YEAR= 2012
NDA 202236 (label) INN (AZELASTINE HYDROCHLORIDE ; FLUTICASONE PROPIONATE) DYMISTA (MYLAN SPECIALITY LP) APPROVAL= AP YEAR= 2012
NDA 091553 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2013
NDA 205434 (label) INN (FLUTICASONE PROPIONATE) FLONASE ALLERGY RELIEF (HALEON US HOLDINGS) APPROVAL= AP YEAR= 2014
NDA 207957 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (HIKMA) APPROVAL= AP YEAR= 2016
NDA 208150 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (APOTEX) APPROVAL= AP YEAR= 2016
NDA 207712 (pdf not found) INN (AZELASTINE HYDROCHLORIDE ; FLUTICASONE PROPIONATE) AZELASTINE HYDROCHLORIDE AND FLUTICASONE PROPIONATE (APOTEX) APPROVAL= AP YEAR= 2017
NDA 208798 (label) INN (FLUTICASONE PROPIONATE) ARMONAIR RESPICLICK (TEVA PHARM) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 208799 (label) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) AIRDUO RESPICLICK (TEVA PHARM) APPROVAL= AP YEAR= 2017
NDA 209022 (label) INN (FLUTICASONE PROPIONATE) XHANCE (PARATEK PHARMS) APPROVAL= AP YEAR= 2017
NDA 208024 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (HIKMA) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 208891 (label) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) WIXELA INHUB (MYLAN) APPROVAL= AP YEAR= 2019
NDA 203433 (pdf not found) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE (HIKMA) APPROVAL= AP YEAR= 2020
NDA 208111 (pdf not found) INN (AZELASTINE HYDROCHLORIDE ; FLUTICASONE PROPIONATE) AZELASTINE HYDROCHLORIDE AND FLUTICASONE PROPIONATE (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2021
NDA 213948 (pdf not found) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE (TEVA PHARMS USA) APPROVAL= AP YEAR= 2021
NDA 215343 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (BRIGHT) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 217088 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2024
NDA 208436 (pdf not found) INN (AZELASTINE HYDROCHLORIDE ; FLUTICASONE PROPIONATE) AZELASTINE HYDROCHLORIDE AND FLUTICASONE PROPIONATE (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2025
NDA 218321 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (RUBICON RESEARCH) APPROVAL= AP YEAR= 2025
NDA 219060 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (RUBICON RESEARCH) APPROVAL= AP YEAR= 2025
NDA 214464 (pdf not found) INN (FLUTICASONE PROPIONATE ; SALMETEROL XINAFOATE) FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE (RESPIRENT PHARMS) APPROVAL= AP YEAR= 2026
NDA 218742 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (GLENMARK SPECLT) APPROVAL= AP YEAR= 2026
NDA 219602 (pdf not found) INN (FLUTICASONE PROPIONATE) FLUTICASONE PROPIONATE (GLENMARK SPECLT) APPROVAL= AP YEAR= 2026