e-Drug3D

643

cas 86541-75-5

CLASS

CARDIOVASCULAR
ANTIHYPERTENSIVE
ANGIOTENSIN-CONVERTING ENZYME (ACE) INHIBITORS

ROUTE (list)

ORAL

PK parameters

F 37 PERCENT
Tmax 0.75 HOUR
PPB 96.7 PERCENT

MW 423.48
NB_atoms 31
XLogP 1.24
PSA 87.696
NB_HD 1
NB_HA 7
fsp3 0.38
Lipinski(0=no;1=yes) 1

FDA
NDA 019851 (label) INN (BENAZEPRIL HYDROCHLORIDE) LOTENSIN (VALIDUS PHARMS) APPROVAL= AP YEAR= 1991
NDA 020033 (label) INN (BENAZEPRIL HYDROCHLORIDE ; HYDROCHLOROTHIAZIDE) LOTENSIN HCT (VALIDUS PHARMS) APPROVAL= AP YEAR= 1992
NDA 020364 (label) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) LOTREL (SANDOZ) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 076118 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (PRINSTON INC) APPROVAL= AP YEAR= 2004
NDA 076211 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (TEVA) APPROVAL= AP YEAR= 2004
NDA 076267 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (HERITAGE PHARMA) APPROVAL= AP YEAR= 2004
NDA 076333 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 2004
NDA 076342 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE ; HYDROCHLOROTHIAZIDE) BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (ANI PHARMS) APPROVAL= AP YEAR= 2004
NDA 076344 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2004
NDA 076348 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE ; HYDROCHLOROTHIAZIDE) BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (ANI PHARMS) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076402 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2004
NDA 076430 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076476 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (GENPHARM) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076612 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE ; HYDROCHLOROTHIAZIDE) BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (MYLAN PHARMS INC) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076631 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE ; HYDROCHLOROTHIAZIDE) BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (SANDOZ) APPROVAL= AP YEAR= 2004
NDA 076688 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE ; HYDROCHLOROTHIAZIDE) BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 077483 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE ; HYDROCHLOROTHIAZIDE) BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (SUN PHARM INDS LTD) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 021714 (pdf not found) INN (AMLODIPINE MALEATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE MALEATE; BENAZEPRIL HYDROCHLORIDE (DR REDDYS LABS LTD) APPROVAL= TA YEAR= 2006
NDA 076820 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2006
NDA 077128 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (COREPHARMA) APPROVAL= AP YEAR= 2006
NDA 077179 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (TEVA PHARMS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 078212 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2008
NDA 078848 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE) BENAZEPRIL HYDROCHLORIDE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2008
NDA 077375 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 078381 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 077183 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (DR REDDYS LABS INC) APPROVAL= AP YEAR= 2010
NDA 078466 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (LUPIN PHARMS) APPROVAL= AP YEAR= 2010
NDA 077890 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 2010
NDA 079047 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (PHARMOBEDIENT) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 090364 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (WATSON LABS INC) APPROVAL= AP YEAR= 2011
NDA 090149 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (DR REDDYS LABS INC) APPROVAL= AP YEAR= 2011
NDA 202239 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2012
NDA 078652 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE (ZYDUS PHARMS USA INC) APPROVAL= TA YEAR= 2013
NDA 091431 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (HERITAGE) APPROVAL= AP YEAR= 2013
NDA 078794 (pdf not found) INN (BENAZEPRIL HYDROCHLORIDE ; HYDROCHLOROTHIAZIDE) BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE (APOTEX) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 077215 (pdf not found) INN (AMLODIPINE BESYLATE ; BENAZEPRIL HYDROCHLORIDE) AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE (AMNEAL) APPROVAL= AP YEAR= 2018 DISCONTINUED