e-Drug3D

627

MORICIZINE

DISCONTINUED

INN
MORICIZINE

cas 31883-05-3

CLASS

CARDIOVASCULAR
ANTIARRHYTHMIC

ROUTE (list)

ORAL

ATC code

C01BG01

PK parameters

F 36 PERCENT
Tmax 0.8 HOUR
VD 300 LITER (PMID8568009)
Cl 150 LITER / HOUR (PMID10434234)
PPB 93.5 PERCENT (PMID8568009)
t1/2 1.9 HOUR

Target

TARGET SODIUM CHANNEL

Sodium channel protein type 5 subunit alpha UNIPROT Q14524 SCN5A

Download SDF file

ethyl N-[10-(3-morpholin-4-ylpropanoyl)phenothiazin-2-yl]carbamate

Formula:
C22H25N3O4S

Calculated chemical properties:

MW 427.52
NB_atoms 30
XLogP 4.11
PSA 69.482
NB_HD 1
NB_HA 7
fsp3 0.36
Lipinski(0=no;1=yes) 1

FDA
NDA 019753 (pdf not found) INN (MORICIZINE HYDROCHLORIDE) ETHMOZINE (SHIRE) APPROVAL= AP YEAR= 1990 NEWMOLECULARENTITY DISCONTINUED