e-Drug3D

608

PREDNICARBATE

INN
PREDNICARBATE

cas 73771-04-7

CLASS

DERMATOLOGICAL
GLUCOCORTICOID
ANTIINFLAMMATORY
CORTICOSTEROID
STEROIDAL
ANTI-PRURITIC

ROUTE (list)

TOPICAL

ATC code

D07AC18

PK parameters

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

TARGET GLUCOCORTICOID RECEPTOR

DrugCentral

Glucocorticoid receptor UNIPROT P04150 NR3C1

Download SDF file

[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] propanoate

Formula:
C27H36O8

Calculated chemical properties:

MW 488.56
NB_atoms 35
XLogP 3.70
PSA 104.006
NB_HD 1
NB_HA 8
fsp3 0.70
Lipinski(0=no;1=yes) 1

FDA
NDA 019568 (label) INN (PREDNICARBATE) DERMATOP (VALEANT PHARMS NORTH) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 020279 (label) INN (PREDNICARBATE) DERMATOP E EMOLLIENT (VALEANT BERMUDA) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 077287 (pdf not found) INN (PREDNICARBATE) PREDNICARBATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 077236 (pdf not found) INN (PREDNICARBATE) PREDNICARBATE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2007