e-Drug3D
576
DICLOFENAC
INN
DICLOFENAC
cas 15307-86-5
CLASS
MUSCULO-SKELETAL
ANTIINFLAMMATORY
CYCLOOXYGENASE INHIBITORS
NONSTEROIDAL ANTIINFLAMMATORY AGENTS (NSAIDS)
ANALGESIC
ANTIPYRETIC
ROUTE (list)
ORAL OPHTHALMIC TOPICAL INTRAVENOUS
PK parameters
F 50 PERCENT
Tmax 2.3 HOUR
VD 91 LITER (65 KILOGRAM)
Cl 34.9 LITER / HOUR
PPB 99 PERCENT
t1/2 2.3 HOUR
Solubility
SPARINGLY SOLUBLE IN WATER
TARGET PROSTAGLANDIN G/H SYNTHASE 1
PROSTAGLANDIN G/H SYNTHASE 2
PROSTAGLANDIN G/H SYNTHASE 2
PDB
3IB0 (STRUCTURAL BASIS OF THE PREVENTION OF NSAID-INDUCED DAMAGE OF THE GASTROINTESTINAL TRACT BY C-TERMINAL HALF (C-LOBE) OF BOVINE COLOSTRUM PROTEIN LACTOFERRIN: BINDING AND STRUCTURAL STUDIES OF C-LOBE COMPLEX WITH DICLOFENAC)
Ligand code = DIF (link to the list of PDB complexes)
Download experimental 3D coordinates of DIF with added hydrogens
Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2
Prostaglandin G,H synthase 1 UNIPROT P23219 PTGS1
Formula:
C14H11Cl2NO2
Calculated chemical properties:
MW 295.13
NB_atoms 19
XLogP 3.03
PSA 46.105
NB_HD 1
NB_HA 3
fsp3 0.07
Lipinski(0=no;1=yes) 1
NB_atoms 19
XLogP 3.03
PSA 46.105
NB_HD 1
NB_HA 3
fsp3 0.07
Lipinski(0=no;1=yes) 1
FDA
NDA 019201 (label) INN (DICLOFENAC SODIUM) VOLTAREN (NOVARTIS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 020037 (label) INN (DICLOFENAC SODIUM) VOLTAREN (NOVARTIS) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 020142 (label) INN (DICLOFENAC POTASSIUM) CATAFLAM (NOVARTIS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074376 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074391 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ROXANE) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074394 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 020254 (label) INN (DICLOFENAC SODIUM) VOLTAREN-XR (NOVARTIS) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074390 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (TEVA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074514 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 1996
NDA 020607 (label) INN (DICLOFENAC SODIUM ; MISOPROSTOL) ARTHROTEC (PFIZER) APPROVAL= AP YEAR= 1997
NDA 074459 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (TEVA PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 020809 (label) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (FALCON PHARMS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075152 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (WATSON LABS TEVA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075185 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (CARLSBAD) APPROVAL= AP YEAR= 1998
NDA 075219 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (TEVA) APPROVAL= AP YEAR= 1998
NDA 075229 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (RUBICON RESEARCH) APPROVAL= AP YEAR= 1998
NDA 074432 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (PLIVA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 074723 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (TEVA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 074986 (label) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (MICRO LABS) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075463 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (RISING) APPROVAL= AP YEAR= 1999
NDA 021005 (label) INN (DICLOFENAC SODIUM) SOLARAZE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075492 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (VPNA) APPROVAL= AP YEAR= 2000
NDA 075582 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (CHARTWELL RX) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 076152 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075281 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2002
NDA 075470 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 075910 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 076201 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (DEXCEL LTD) APPROVAL= AP YEAR= 2002
NDA 076561 (pdf not found) INN (DICLOFENAC POTASSIUM) CATAFLAM (AMICI PHARMA) APPROVAL= AP YEAR= 2004
NDA 021234 (label) INN (DICLOFENAC EPOLAMINE) FLECTOR (IBSA) APPROVAL= AP YEAR= 2007
NDA 022122 (label) INN (DICLOFENAC SODIUM) VOLTAREN ARTHRITIS PAIN (HALEON US HOLDINGS) APPROVAL= AP YEAR= 2007
NDA 077863 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (UNIQUE) APPROVAL= AP YEAR= 2007
NDA 078553 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (RISING) APPROVAL= AP YEAR= 2007
NDA 078792 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (BAUSCH AND LOMB) APPROVAL= AP YEAR= 2007
NDA 077600 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (RUBICON RESEARCH) APPROVAL= AP YEAR= 2008
NDA 077845 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (SCIEGEN PHARMS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078031 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (SANDOZ) APPROVAL= AP YEAR= 2008
NDA 020947 (label) INN (DICLOFENAC SODIUM) PENNSAID (NUVO PHARMS INC) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 022165 (label) INN (DICLOFENAC POTASSIUM) CAMBIA (COSETTE) APPROVAL= AP YEAR= 2009
NDA 022202 (label) INN (DICLOFENAC POTASSIUM) ZIPSOR (COSETTE) APPROVAL= AP YEAR= 2009
NDA 090066 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (UNIQUE) APPROVAL= AP YEAR= 2010
NDA 201089 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2012
NDA 200158 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (SANDOZ) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 200936 (label) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AMNEAL) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 204592 (label) INN (DICLOFENAC) ZORVOLEX (ZYLA) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202393 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (TWI PHARMS) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 022396 (label) INN (DICLOFENAC SODIUM) DYLOJECT (JAVELIN PHARMS INC) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 200540 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (EXELA HOLDINGS) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202027 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (APOTEX) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202852 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (WATSON LABS INC) APPROVAL= AP YEAR= 2014
NDA 203818 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (SUN PHARMA CANADA) APPROVAL= AP YEAR= 2014
NDA 204623 (label) INN (DICLOFENAC SODIUM) PENNSAID (HORIZON) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202769 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (PAI HOLDINGS PHARM) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 203383 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ALTAIRE PHARMS INC) APPROVAL= AP YEAR= 2015
NDA 204132 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (LUPIN) APPROVAL= AP YEAR= 2015
NDA 205878 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (NOVEL LABS INC) APPROVAL= AP YEAR= 2015
NDA 206493 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 2015
NDA 208068 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (PADDOCK LABS) APPROVAL= TA YEAR= 2015
NDA 202964 (label) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (PH HEALTH) APPROVAL= AP YEAR= 2016
NDA 204648 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (BIONPHARMA) APPROVAL= AP YEAR= 2016
NDA 206298 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (SUN PHARMA CANADA) APPROVAL= AP YEAR= 2016
NDA 208077 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AMNEAL PHARMS) APPROVAL= AP YEAR= 2016
NDA 203786 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (VERSAPHARM INC) APPROVAL= TA YEAR= 2016
NDA 203995 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (AMNEAL PHARMS) APPROVAL= AP YEAR= 2016
NDA 206116 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AMNEAL PHARMS) APPROVAL= AP YEAR= 2016
NDA 207393 (pdf not found) INN (DICLOFENAC) DICLOFENAC (LUPIN LTD) APPROVAL= TA YEAR= 2016
NDA 208301 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2016
NDA 206715 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (RISING) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207238 (label) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ACTAVIS LABS UT INC) APPROVAL= TA YEAR= 2017
NDA 206411 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2018
NDA 206976 (label) INN (DICLOFENAC EPOLAMINE) LICART (IBSA INST BIO) APPROVAL= AP YEAR= 2018
NDA 209484 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (HIKMA) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 209903 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (CIPLA) APPROVAL= AP YEAR= 2018
NDA 210893 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2018
NDA 204306 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AUROLIFE PHARMA LLC) APPROVAL= AP YEAR= 2019
NDA 211253 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (PERRIGO PHARMA INTL) APPROVAL= AP YEAR= 2019
NDA 208786 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (RISING) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 210078 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (ONESOURCE SPECIALTY) APPROVAL= AP YEAR= 2019
NDA 205143 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (YUNG SHIN PHARM) APPROVAL= AP YEAR= 2020
NDA 210986 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ENCUBE) APPROVAL= AP YEAR= 2020
NDA 206655 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2021
NDA 204355 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (MICRO LABS) APPROVAL= AP YEAR= 2021
NDA 213875 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2021
NDA 215585 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (INGENUS PHARMS LLC) APPROVAL= AP YEAR= 2021
NDA 208021 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (LUPIN PHARMS) APPROVAL= AP YEAR= 2022
NDA 208098 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (SUN PHARMA CANADA) APPROVAL= AP YEAR= 2022
NDA 208198 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AMNEAL) APPROVAL= AP YEAR= 2022
NDA 207714 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (APOTEX) APPROVAL= AP YEAR= 2022
NDA 215375 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (ANNORA PHARMA) APPROVAL= AP YEAR= 2022
NDA 215750 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (UMEDICA) APPROVAL= AP YEAR= 2022
NDA 212351 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ALEMBIC) APPROVAL= AP YEAR= 2022
NDA 212506 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ALEMBIC) APPROVAL= AP YEAR= 2022
NDA 216275 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (INGENUS PHARMS LLC) APPROVAL= AP YEAR= 2022
NDA 216635 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (ALKEM LABS LTD) APPROVAL= AP YEAR= 2022
NDA 206771 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (ZYDUS PHARMS) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 213040 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AUROLIFE PHARMA LLC) APPROVAL= AP YEAR= 2023
NDA 215787 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (SENORES PHARMS) APPROVAL= AP YEAR= 2023
NDA 216548 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (RUBICON RESEARCH) APPROVAL= AP YEAR= 2023
NDA 218011 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (TARO) APPROVAL= AP YEAR= 2024
NDA 215891 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (TORRENT) APPROVAL= AP YEAR= 2025
NDA 217646 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ENCUBE) APPROVAL= AP YEAR= 2025
NDA 217010 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (UMEDICA) APPROVAL= AP YEAR= 2025
NDA 219945 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (UMEDICA) APPROVAL= AP YEAR= 2025
NDA 019201 (label) INN (DICLOFENAC SODIUM) VOLTAREN (NOVARTIS) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 020037 (label) INN (DICLOFENAC SODIUM) VOLTAREN (NOVARTIS) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 020142 (label) INN (DICLOFENAC POTASSIUM) CATAFLAM (NOVARTIS) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 074376 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074391 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ROXANE) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074394 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (CHARTWELL RX) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 020254 (label) INN (DICLOFENAC SODIUM) VOLTAREN-XR (NOVARTIS) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074390 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (TEVA) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074514 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 1996
NDA 020607 (label) INN (DICLOFENAC SODIUM ; MISOPROSTOL) ARTHROTEC (PFIZER) APPROVAL= AP YEAR= 1997
NDA 074459 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (TEVA PHARMS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 020809 (label) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (FALCON PHARMS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075152 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (WATSON LABS TEVA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075185 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (CARLSBAD) APPROVAL= AP YEAR= 1998
NDA 075219 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (TEVA) APPROVAL= AP YEAR= 1998
NDA 075229 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (RUBICON RESEARCH) APPROVAL= AP YEAR= 1998
NDA 074432 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (PLIVA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 074723 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (TEVA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 074986 (label) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (MICRO LABS) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075463 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (RISING) APPROVAL= AP YEAR= 1999
NDA 021005 (label) INN (DICLOFENAC SODIUM) SOLARAZE (FOUGERA PHARMS) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075492 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (VPNA) APPROVAL= AP YEAR= 2000
NDA 075582 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (CHARTWELL RX) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 076152 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075281 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2002
NDA 075470 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 075910 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 076201 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (DEXCEL LTD) APPROVAL= AP YEAR= 2002
NDA 076561 (pdf not found) INN (DICLOFENAC POTASSIUM) CATAFLAM (AMICI PHARMA) APPROVAL= AP YEAR= 2004
NDA 021234 (label) INN (DICLOFENAC EPOLAMINE) FLECTOR (IBSA) APPROVAL= AP YEAR= 2007
NDA 022122 (label) INN (DICLOFENAC SODIUM) VOLTAREN ARTHRITIS PAIN (HALEON US HOLDINGS) APPROVAL= AP YEAR= 2007
NDA 077863 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (UNIQUE) APPROVAL= AP YEAR= 2007
NDA 078553 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (RISING) APPROVAL= AP YEAR= 2007
NDA 078792 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (BAUSCH AND LOMB) APPROVAL= AP YEAR= 2007
NDA 077600 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (RUBICON RESEARCH) APPROVAL= AP YEAR= 2008
NDA 077845 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (SCIEGEN PHARMS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 078031 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (SANDOZ) APPROVAL= AP YEAR= 2008
NDA 020947 (label) INN (DICLOFENAC SODIUM) PENNSAID (NUVO PHARMS INC) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 022165 (label) INN (DICLOFENAC POTASSIUM) CAMBIA (COSETTE) APPROVAL= AP YEAR= 2009
NDA 022202 (label) INN (DICLOFENAC POTASSIUM) ZIPSOR (COSETTE) APPROVAL= AP YEAR= 2009
NDA 090066 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (UNIQUE) APPROVAL= AP YEAR= 2010
NDA 201089 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2012
NDA 200158 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (SANDOZ) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 200936 (label) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AMNEAL) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 204592 (label) INN (DICLOFENAC) ZORVOLEX (ZYLA) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 202393 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (TWI PHARMS) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 022396 (label) INN (DICLOFENAC SODIUM) DYLOJECT (JAVELIN PHARMS INC) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 200540 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (EXELA HOLDINGS) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202027 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (APOTEX) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202852 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (WATSON LABS INC) APPROVAL= AP YEAR= 2014
NDA 203818 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (SUN PHARMA CANADA) APPROVAL= AP YEAR= 2014
NDA 204623 (label) INN (DICLOFENAC SODIUM) PENNSAID (HORIZON) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 202769 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (PAI HOLDINGS PHARM) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 203383 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ALTAIRE PHARMS INC) APPROVAL= AP YEAR= 2015
NDA 204132 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (LUPIN) APPROVAL= AP YEAR= 2015
NDA 205878 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (NOVEL LABS INC) APPROVAL= AP YEAR= 2015
NDA 206493 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 2015
NDA 208068 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (PADDOCK LABS) APPROVAL= TA YEAR= 2015
NDA 202964 (label) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (PH HEALTH) APPROVAL= AP YEAR= 2016
NDA 204648 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (BIONPHARMA) APPROVAL= AP YEAR= 2016
NDA 206298 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (SUN PHARMA CANADA) APPROVAL= AP YEAR= 2016
NDA 208077 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AMNEAL PHARMS) APPROVAL= AP YEAR= 2016
NDA 203786 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (VERSAPHARM INC) APPROVAL= TA YEAR= 2016
NDA 203995 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (AMNEAL PHARMS) APPROVAL= AP YEAR= 2016
NDA 206116 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AMNEAL PHARMS) APPROVAL= AP YEAR= 2016
NDA 207393 (pdf not found) INN (DICLOFENAC) DICLOFENAC (LUPIN LTD) APPROVAL= TA YEAR= 2016
NDA 208301 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (GLENMARK PHARMS LTD) APPROVAL= AP YEAR= 2016
NDA 206715 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (RISING) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207238 (label) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ACTAVIS LABS UT INC) APPROVAL= TA YEAR= 2017
NDA 206411 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2018
NDA 206976 (label) INN (DICLOFENAC EPOLAMINE) LICART (IBSA INST BIO) APPROVAL= AP YEAR= 2018
NDA 209484 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (HIKMA) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 209903 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (CIPLA) APPROVAL= AP YEAR= 2018
NDA 210893 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (PADAGIS ISRAEL) APPROVAL= AP YEAR= 2018
NDA 204306 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AUROLIFE PHARMA LLC) APPROVAL= AP YEAR= 2019
NDA 211253 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (PERRIGO PHARMA INTL) APPROVAL= AP YEAR= 2019
NDA 208786 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (RISING) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 210078 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (ONESOURCE SPECIALTY) APPROVAL= AP YEAR= 2019
NDA 205143 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (YUNG SHIN PHARM) APPROVAL= AP YEAR= 2020
NDA 210986 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ENCUBE) APPROVAL= AP YEAR= 2020
NDA 206655 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2021
NDA 204355 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (MICRO LABS) APPROVAL= AP YEAR= 2021
NDA 213875 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2021
NDA 215585 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (INGENUS PHARMS LLC) APPROVAL= AP YEAR= 2021
NDA 208021 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (LUPIN PHARMS) APPROVAL= AP YEAR= 2022
NDA 208098 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (SUN PHARMA CANADA) APPROVAL= AP YEAR= 2022
NDA 208198 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AMNEAL) APPROVAL= AP YEAR= 2022
NDA 207714 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (APOTEX) APPROVAL= AP YEAR= 2022
NDA 215375 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (ANNORA PHARMA) APPROVAL= AP YEAR= 2022
NDA 215750 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (UMEDICA) APPROVAL= AP YEAR= 2022
NDA 212351 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ALEMBIC) APPROVAL= AP YEAR= 2022
NDA 212506 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ALEMBIC) APPROVAL= AP YEAR= 2022
NDA 216275 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (INGENUS PHARMS LLC) APPROVAL= AP YEAR= 2022
NDA 216635 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (ALKEM LABS LTD) APPROVAL= AP YEAR= 2022
NDA 206771 (pdf not found) INN (DICLOFENAC SODIUM ; MISOPROSTOL) DICLOFENAC SODIUM AND MISOPROSTOL (ZYDUS PHARMS) APPROVAL= AP YEAR= 2023 DISCONTINUED
NDA 213040 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (AUROLIFE PHARMA LLC) APPROVAL= AP YEAR= 2023
NDA 215787 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (SENORES PHARMS) APPROVAL= AP YEAR= 2023
NDA 216548 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (RUBICON RESEARCH) APPROVAL= AP YEAR= 2023
NDA 218011 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (TARO) APPROVAL= AP YEAR= 2024
NDA 215891 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (TORRENT) APPROVAL= AP YEAR= 2025
NDA 217646 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (ENCUBE) APPROVAL= AP YEAR= 2025
NDA 217010 (pdf not found) INN (DICLOFENAC POTASSIUM) DICLOFENAC POTASSIUM (UMEDICA) APPROVAL= AP YEAR= 2025
NDA 219945 (pdf not found) INN (DICLOFENAC SODIUM) DICLOFENAC SODIUM (UMEDICA) APPROVAL= AP YEAR= 2025