e-Drug3D

568

cas 466-99-9

CLASS

NERVOUS SYSTEM
ANALGESIC
NARCOTICS

ROUTE (list)

INJECTION ORAL INTRAMUSCULAR INTRAVENOUS SUBCUTANEOUS

PK parameters

Tmax 0.73 HOUR
Cmax 20 NANOMOLAR
VD 302.9 LITER
Cl 117.6 LITER / HOUR
PPB 13 PERCENT
t1/2 2.3 HOUR

MW 285.33
NB_atoms 21
XLogP 1.63
PSA 55.185
NB_HD 1
NB_HA 4
fsp3 0.59
Lipinski(0=no;1=yes) 1

FDA
NDA 019034 (label) INN (HYDROMORPHONE HYDROCHLORIDE) DILAUDID-HP (FRESENIUS KABI USA) APPROVAL= AP YEAR= 1984
NDA 019891 (label) INN (HYDROMORPHONE HYDROCHLORIDE) DILAUDID (RHODES PHARMS) APPROVAL= AP YEAR= 1992
NDA 019892 (label) INN (HYDROMORPHONE HYDROCHLORIDE) DILAUDID (RHODES PHARMS) APPROVAL= AP YEAR= 1992
NDA 074317 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074598 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074597 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074653 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 1998
NDA 076444 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (BARR) APPROVAL= AP YEAR= 2003 DISCONTINUED
NDA 021044 (label) INN (HYDROMORPHONE HYDROCHLORIDE) PALLADONE (PURDUE PHARMA LP) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 076855 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (SPECGX LLC) APPROVAL= AP YEAR= 2004
NDA 076723 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (MPP PHARMA) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 077311 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (NESHER PHARMS) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 078273 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (MALLINCKRODT INC) APPROVAL= AP YEAR= 2007 OBSOLETE
NDA 078591 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (HOSPIRA INC) APPROVAL= AP YEAR= 2008
NDA 077471 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (GENUS) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 078439 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (LANNETT) APPROVAL= AP YEAR= 2009
NDA 021217 (label) INN (HYDROMORPHONE HYDROCHLORIDE) EXALGO (SPECGX LLC) APPROVAL= AP YEAR= 2010 DISCONTINUED
NDA 078228 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2010
NDA 078261 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2010
NDA 200403 (label) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (HOSPIRA INC) APPROVAL= AP YEAR= 2011
NDA 202144 (label) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (ACTAVIS LABS FL INC) APPROVAL= AP YEAR= 2014 DISCONTINUED
NDA 204278 (label) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (PADAGIS US) APPROVAL= AP YEAR= 2015
NDA 205814 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (AUROLIFE PHARMA LLC) APPROVAL= AP YEAR= 2016
NDA 205629 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (OSMOTICA PHARM US) APPROVAL= AP YEAR= 2016
NDA 210176 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (ASCENT PHARMS INC) APPROVAL= AP YEAR= 2017
NDA 202159 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2018
NDA 210506 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (ASCENT PHARMS INC) APPROVAL= AP YEAR= 2018
NDA 207108 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (GENUS) APPROVAL= AP YEAR= 2020 DISCONTINUED
NDA 212133 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (ASCENT PHARMS INC) APPROVAL= AP YEAR= 2020
NDA 217812 (label) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2023
NDA 216899 (pdf not found) INN (HYDROMORPHONE HYDROCHLORIDE) HYDROMORPHONE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 2024