e-Drug3D
469
CIMETIDINE
INN
CIMETIDINE
cas 51481-61-9
CLASS
METABOLISM
HISTAMINE H2 RECEPTOR BLOCKER
ANTIHISTAMINE
INHIBIT GASTRIC ACID SECRETION
ROUTE (list)
ORAL INJECTION
PK parameters
Tmax 1.1 HOUR
VD 78 LITER (65 KILOGRAM)
Cl 31.6 LITER / HOUR (65 KILOGRAM)
PPB 22 PERCENT
t1/2 2 HOUR
Solubility
SLIGHTLY SOLUBLE IN WATER
TARGET HISTAMINE H2 RECEPTOR
Histamine H2 receptor UNIPROT P25021 HRH2
Formula:
C10H16N6S
Calculated chemical properties:
MW 252.36
NB_atoms 17
XLogP 0.60
PSA 77.484
NB_HD 3
NB_HA 6
fsp3 0.50
Lipinski(0=no;1=yes) 1
NB_atoms 17
XLogP 0.60
PSA 77.484
NB_HD 3
NB_HA 6
fsp3 0.50
Lipinski(0=no;1=yes) 1
FDA
NDA 017920 (pdf not found) INN (CIMETIDINE) TAGAMET (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 017924 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) TAGAMET (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 017939 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) TAGAMET (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 019434 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) TAGAMET HYDROCHLORIDE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 074005 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074151 (pdf not found) INN (CIMETIDINE) CIMETIDINE (TEVA) APPROVAL= AP YEAR= 1994
NDA 074176 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (G AND W LABS INC) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074246 (pdf not found) INN (CIMETIDINE) CIMETIDINE (MYLAN) APPROVAL= AP YEAR= 1994
NDA 074251 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 1994
NDA 074269 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER (HOSPIRA) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074281 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CHARTWELL MOLECULES) APPROVAL= AP YEAR= 1994 DISCONTINUED OBSOLETE
NDA 074329 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CHARTWELL MOLECULES) APPROVAL= AP YEAR= 1994
NDA 074353 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (LUITPOLD) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074361 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CYCLE) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074371 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CYCLE) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074463 (pdf not found) INN (CIMETIDINE) CIMETIDINE (TEVA) APPROVAL= AP YEAR= 1994
NDA 074468 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER (HOSPIRA) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 020238 (label) INN (CIMETIDINE) TAGAMET HB (MEDTECH PRODUCTS) APPROVAL= AP YEAR= 1995
NDA 074100 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CHARTWELL RX) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074250 (pdf not found) INN (CIMETIDINE) CIMETIDINE (SANDOZ) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074339 (pdf not found) INN (CIMETIDINE) CIMETIDINE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074340 (pdf not found) INN (CIMETIDINE) CIMETIDINE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074344 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074345 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074365 (pdf not found) INN (CIMETIDINE) CIMETIDINE (TEVA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074401 (pdf not found) INN (CIMETIDINE) CIMETIDINE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074402 (pdf not found) INN (CIMETIDINE) CIMETIDINE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074422 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074424 (pdf not found) INN (CIMETIDINE) CIMETIDINE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074316 (pdf not found) INN (CIMETIDINE) CIMETIDINE (WATSON LABS INC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074349 (pdf not found) INN (CIMETIDINE) CIMETIDINE (WATSON LABS INC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074428 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074506 (pdf not found) INN (CIMETIDINE) CIMETIDINE (UPSHER SMITH LABS) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074610 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074252 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (TEVA PARENTERAL) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074296 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074412 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074541 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (CYCLE) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074553 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PHARM ASSOC) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074566 (pdf not found) INN (CIMETIDINE) CIMETIDINE (PLIVA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074568 (pdf not found) INN (CIMETIDINE) CIMETIDINE (PLIVA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074664 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PAI HOLDINGS PHARM) APPROVAL= AP YEAR= 1997
NDA 074757 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PHARMOBEDIENT CNSLTG) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074859 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074890 (label) INN (CIMETIDINE) CIMETIDINE (HIKMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074948 (pdf not found) INN (CIMETIDINE) CIMETIDINE (APOTEX) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074961 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CONTRACT PHARMACAL) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074963 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CONTRACT PHARMACAL) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074972 (pdf not found) INN (CIMETIDINE) CIMETIDINE (PERRIGO) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075110 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075122 (pdf not found) INN (CIMETIDINE) CIMETIDINE (SANDOZ) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075285 (pdf not found) INN (CIMETIDINE) CIMETIDINE (L PERRIGO CO) APPROVAL= AP YEAR= 1998
NDA 020951 (label) INN (CIMETIDINE) TAGAMET HB 200 (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075345 (pdf not found) INN (CIMETIDINE) CIMETIDINE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075425 (pdf not found) INN (CIMETIDINE) CIMETIDINE (WATSON LABS TEVA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075560 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PHARM ASSOC) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 218220 (pdf not found) INN (CIMETIDINE) CIMETIDINE (BIONPHARMA) APPROVAL= AP YEAR= 2024
NDA 218997 (pdf not found) INN (CIMETIDINE) CIMETIDINE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2024
NDA 017920 (pdf not found) INN (CIMETIDINE) TAGAMET (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 017924 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) TAGAMET (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 017939 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) TAGAMET (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 019434 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) TAGAMET HYDROCHLORIDE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 074005 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074151 (pdf not found) INN (CIMETIDINE) CIMETIDINE (TEVA) APPROVAL= AP YEAR= 1994
NDA 074176 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (G AND W LABS INC) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074246 (pdf not found) INN (CIMETIDINE) CIMETIDINE (MYLAN) APPROVAL= AP YEAR= 1994
NDA 074251 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 1994
NDA 074269 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER (HOSPIRA) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074281 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CHARTWELL MOLECULES) APPROVAL= AP YEAR= 1994 DISCONTINUED OBSOLETE
NDA 074329 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CHARTWELL MOLECULES) APPROVAL= AP YEAR= 1994
NDA 074353 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (LUITPOLD) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074361 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CYCLE) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074371 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CYCLE) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 074463 (pdf not found) INN (CIMETIDINE) CIMETIDINE (TEVA) APPROVAL= AP YEAR= 1994
NDA 074468 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER (HOSPIRA) APPROVAL= AP YEAR= 1994 DISCONTINUED
NDA 020238 (label) INN (CIMETIDINE) TAGAMET HB (MEDTECH PRODUCTS) APPROVAL= AP YEAR= 1995
NDA 074100 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CHARTWELL RX) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074250 (pdf not found) INN (CIMETIDINE) CIMETIDINE (SANDOZ) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074339 (pdf not found) INN (CIMETIDINE) CIMETIDINE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074340 (pdf not found) INN (CIMETIDINE) CIMETIDINE (NOVITIUM PHARMA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074344 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074345 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074365 (pdf not found) INN (CIMETIDINE) CIMETIDINE (TEVA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074401 (pdf not found) INN (CIMETIDINE) CIMETIDINE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074402 (pdf not found) INN (CIMETIDINE) CIMETIDINE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074422 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074424 (pdf not found) INN (CIMETIDINE) CIMETIDINE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1995 DISCONTINUED
NDA 074316 (pdf not found) INN (CIMETIDINE) CIMETIDINE (WATSON LABS INC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074349 (pdf not found) INN (CIMETIDINE) CIMETIDINE (WATSON LABS INC) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074428 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PH HEALTH) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074506 (pdf not found) INN (CIMETIDINE) CIMETIDINE (UPSHER SMITH LABS) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074610 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1996 DISCONTINUED
NDA 074252 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (TEVA PARENTERAL) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074296 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074412 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (HOSPIRA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074541 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (CYCLE) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074553 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PHARM ASSOC) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074566 (pdf not found) INN (CIMETIDINE) CIMETIDINE (PLIVA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074568 (pdf not found) INN (CIMETIDINE) CIMETIDINE (PLIVA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074664 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PAI HOLDINGS PHARM) APPROVAL= AP YEAR= 1997
NDA 074757 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PHARMOBEDIENT CNSLTG) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 074859 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074890 (label) INN (CIMETIDINE) CIMETIDINE (HIKMA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074948 (pdf not found) INN (CIMETIDINE) CIMETIDINE (APOTEX) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074961 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CONTRACT PHARMACAL) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074963 (pdf not found) INN (CIMETIDINE) CIMETIDINE (CONTRACT PHARMACAL) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 074972 (pdf not found) INN (CIMETIDINE) CIMETIDINE (PERRIGO) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075110 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075122 (pdf not found) INN (CIMETIDINE) CIMETIDINE (SANDOZ) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 075285 (pdf not found) INN (CIMETIDINE) CIMETIDINE (L PERRIGO CO) APPROVAL= AP YEAR= 1998
NDA 020951 (label) INN (CIMETIDINE) TAGAMET HB 200 (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075345 (pdf not found) INN (CIMETIDINE) CIMETIDINE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075425 (pdf not found) INN (CIMETIDINE) CIMETIDINE (WATSON LABS TEVA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 075560 (pdf not found) INN (CIMETIDINE HYDROCHLORIDE) CIMETIDINE HYDROCHLORIDE (PHARM ASSOC) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 218220 (pdf not found) INN (CIMETIDINE) CIMETIDINE (BIONPHARMA) APPROVAL= AP YEAR= 2024
NDA 218997 (pdf not found) INN (CIMETIDINE) CIMETIDINE (AUROBINDO PHARMA LTD) APPROVAL= AP YEAR= 2024