e-Drug3D

319

ETHIONAMIDE

DISCONTINUED

INN
ETHIONAMIDE

cas 536-33-4

CLASS

ANTIINFECTIVES
TUBERCULOSTATIC
ANTIFUNGAL
ANTIBIOTIC
ANTIBACTERIAL
ANTITUBERCULAR AGENTS
FATTY ACID SYNTHESIS INHIBITORS
LEPROSTATIC AGENTS

ROUTE (list)

ORAL

ATC code

J04AD03

PK parameters

Tmax 1.02 HOUR
Cmax 13 MICROMOLAR
VD 93.5 LITER
Cl 33.7 LITER / HOUR (EQN)
PPB 30 PERCENT
t1/2 1.92 HOUR

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

TARGET ETHA-ENCODED NADPH-SPECIFIC FAD-CONTAINING MONO-OXYGENASE (ETHA) (PMID20974869)

Enoyl-acyl-carrier-protein reductase NADH UNIPROT P9WGR1 inhA

Download SDF file

2-ethylpyridine-4-carbothioamide

Formula:
C8H10N2S

Calculated chemical properties:

MW 166.25
NB_atoms 11
XLogP 1.28
PSA 33.665
NB_HD 2
NB_HA 2
fsp3 0.25
Lipinski(0=no;1=yes) 1

FDA
NDA 013026 (label) INN (ETHIONAMIDE) TRECATOR (WYETH PHARMS) APPROVAL= AP YEAR= 1965 DISCONTINUED