e-Drug3D

303

cas 129-03-3

CLASS

RESPIRATORY SYSTEM
ANTIHISTAMINE
ANTISEROTONERGIC AGENT
ANTI-ALLERGIC AGENTS
HISTAMINE H1 ANTAGONISTS
SEROTONIN ANTAGONISTS
ANTICHOLINERGIC
SEDATIVE

ROUTE (list)

ORAL

PK parameters

Tmax 7.5 HOUR
t1/2 12.5 HOUR

TARGET HISTAMINE H1 RECEPTOR
5-HYDROXYTRYPTAMINE 2A RECEPTOR

PDB
5AYF (CRYSTAL STRUCTURE OF SET7, 9 IN COMPLEX WITH CYPROHEPTADINE)

Ligand code = C7H (link to the list of PDB complexes)

Download experimental 3D coordinates of C7H with added hydrogens

MW 287.39
NB_atoms 22
XLogP 4.70
PSA 5.755
NB_HD 0
NB_HA 1
fsp3 0.24
Lipinski(0=no;1=yes) 1

FDA
NDA 085245 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086165 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087001 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (MORTON GROVE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087566 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (MD PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087685 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (ASCOT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087839 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (PIONEER PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088798 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (AM THERAP) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 012649 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) PERIACTIN (MERCK) APPROVAL= AP YEAR= 1961 DISCONTINUED
NDA 013220 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) PERIACTIN (MERCK) APPROVAL= AP YEAR= 1962 DISCONTINUED
NDA 086678 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (MYLAN) APPROVAL= AP YEAR= 1979 DISCONTINUED
NDA 086737 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (KV PHARM) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 086833 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (ACTAVIS MID ATLANTIC) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 087056 (label) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (HERITAGE PHARMA) APPROVAL= AP YEAR= 1980 DISCONTINUED
NDA 086580 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 086808 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087129 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (STRIDES PHARMA INTL) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087405 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (SUPERPHARM) APPROVAL= AP YEAR= 1981 DISCONTINUED
NDA 087284 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (VITARINE) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088205 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (PLIVA) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 088212 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 1983
NDA 088232 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (DURAMED PHARMS BARR) APPROVAL= AP YEAR= 1983 DISCONTINUED
NDA 089057 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (HALSEY) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089199 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (HALSEY) APPROVAL= AP YEAR= 1986 DISCONTINUED
NDA 089021 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (NASKA) APPROVAL= AP YEAR= 1987 DISCONTINUED
NDA 040537 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (MOUNTAIN) APPROVAL= AP YEAR= 2003
NDA 040644 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (KENTON) APPROVAL= AP YEAR= 2006
NDA 040668 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2006
NDA 091295 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (PHARM ASSOC) APPROVAL= AP YEAR= 2013 DISCONTINUED
NDA 205087 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (INGENUS PHARMS LLC) APPROVAL= AP YEAR= 2015
NDA 204823 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (PATRIN) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 206553 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (APPCO) APPROVAL= AP YEAR= 2016
NDA 207783 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 203191 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (CHARTWELL MOLECULAR) APPROVAL= AP YEAR= 2017
NDA 207555 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 2017
NDA 208938 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2017
NDA 209172 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (STRIDES PHARMA INTL) APPROVAL= AP YEAR= 2018
NDA 209108 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (ST JOHN PHARM) APPROVAL= AP YEAR= 2018
NDA 206676 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (REGCON HOLDINGS) APPROVAL= AP YEAR= 2019
NDA 212423 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (QUAGEN) APPROVAL= AP YEAR= 2019
NDA 212491 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (QUAGEN) APPROVAL= AP YEAR= 2021
NDA 205431 (pdf not found) INN (CYPROHEPTADINE HYDROCHLORIDE) CYPROHEPTADINE HYDROCHLORIDE (TRIS PHARMA INC) APPROVAL= AP YEAR= 2021 DISCONTINUED