e-Drug3D
294
cas 156-08-1
CLASS
METABOLISM
ANTIANOREXIC
APPETITE SUPPRESSION
ANORECTIC AGENT
ROUTE (list)
ORAL
ATC code
N06BA01
PK parameters
Solubility
READILY SOLUBLE IN WATER
TARGET NORADRENALINE TRANSPORTER (NAT)
DOPAMINE TRANSPORTER (DAT)
Sodium-dependent noradrenaline transporter UNIPROT P23975 SLC6A2
Sodium-dependent dopamine transporter UNIPROT Q01959 SLC6A3
Formula:
C17H21N
Calculated chemical properties:
MW 239.35
NB_atoms 18
XLogP 3.75
PSA 5.004
NB_HD 0
NB_HA 1
fsp3 0.29
Lipinski(0=no;1=yes) 1
NB_atoms 18
XLogP 3.75
PSA 5.004
NB_HD 0
NB_HA 1
fsp3 0.29
Lipinski(0=no;1=yes) 1
FDA
NDA 012427 (label) INN (BENZPHETAMINE HYDROCHLORIDE) DIDREX (PFIZER) APPROVAL= AP YEAR= 1960 NEWMOLECULARENTITY DISCONTINUED
NDA 040578 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (SCINOPHARM TAIWAN) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 040714 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040747 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (TEDOR PHARM) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040773 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (SPECGX LLC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040845 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 090473 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (CHARTWELL) APPROVAL= AP YEAR= 2010
NDA 090968 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (KVK TECH) APPROVAL= AP YEAR= 2010
NDA 202061 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (AVET LIFESCIENCES) APPROVAL= AP YEAR= 2012
NDA 090346 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2015
NDA 012427 (label) INN (BENZPHETAMINE HYDROCHLORIDE) DIDREX (PFIZER) APPROVAL= AP YEAR= 1960 NEWMOLECULARENTITY DISCONTINUED
NDA 040578 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (SCINOPHARM TAIWAN) APPROVAL= AP YEAR= 2006 DISCONTINUED
NDA 040714 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040747 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (TEDOR PHARM) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040773 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (SPECGX LLC) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 040845 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (IMPAX LABS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 090473 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (CHARTWELL) APPROVAL= AP YEAR= 2010
NDA 090968 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (KVK TECH) APPROVAL= AP YEAR= 2010
NDA 202061 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (AVET LIFESCIENCES) APPROVAL= AP YEAR= 2012
NDA 090346 (pdf not found) INN (BENZPHETAMINE HYDROCHLORIDE) BENZPHETAMINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2015