e-Drug3D

220

TRIFLUPROMAZINE

DISCONTINUED

INN
TRIFLUPROMAZINE

cas 146-54-3

CLASS

NERVOUS SYSTEM
ANTIPSYCHOTIC

ROUTE (list)

ORAL INJECTION

ATC code

N05AA05

PK parameters

Target

TARGET SEROTONIN TRANSPORTER (PMID10193665)

DrugCentral

D(2) dopamine receptor UNIPROT P14416 DRD2

Download SDF file

N,N-dimethyl-3-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-amine

Formula:
C18H19F3N2S

Calculated chemical properties:

MW 352.42
NB_atoms 24
XLogP 5.26
PSA 8.007
NB_HD 0
NB_HA 2
fsp3 0.33
Lipinski(0=no;1=yes) 0

FDA
NDA 011491 (pdf not found) INN (TRIFLUPROMAZINE) VESPRIN (APOTHECON) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 011123 (pdf not found) INN (TRIFLUPROMAZINE HYDROCHLORIDE) VESPRIN (BRISTOL MYERS SQUIBB) APPROVAL= AP YEAR= 1957 NEWMOLECULARENTITY DISCONTINUED
NDA 011325 (pdf not found) INN (TRIFLUPROMAZINE HYDROCHLORIDE) VESPRIN (APOTHECON) APPROVAL= AP YEAR= 1958 DISCONTINUED