e-Drug3D

2188

RELACORILANT

INN
RELACORILANT

cas 1496510-51-0

CLASS

ANTINEOPLASTIC
A GLUCOCORTICOID RECEPTOR ANTAGONIST
TREATMENT OF OVARIAN CANCER

ROUTE (list)

ORAL

ATC code

PK parameters

Tmax 2.5 HOUR
VD 2490 LITER
Cl 52 LITER / HOUR
PPB 99 PERCENT
t1/2 27 HOUR

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

TARGET GLUCOCORTICOID RECEPTOR

DrugCentral

Download SDF file

Methanone, [(4aR)-1-(4-fluorophenyl)-1,4,5,6,7,8-hexahydro-6-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl][4-(trifluoromethyl)-2-pyridinyl]-

Formula:
C27H22F4N6O3S

Calculated chemical properties:

MW 586.58
NB_atoms 41
XLogP 4.06
PSA 90.057
NB_HD 0
NB_HA 9
fsp3 0.26
Lipinski(0=no;1=yes) 0

FDA
NDA 220641 (label) INN (RELACORILANT) LIFYORLI COPACKAGED (CORCEPT THERAP) APPROVAL= AP YEAR= 2026 NEWMOLECULARENTITY