e-Drug3D

2182

TRADIPITANT

INN
TRADIPITANT

cas 622370-35-8

CLASS

NERVOUS SYSTEM
A SUBSTANCE P/NEUROKININ 1 (NK1) RECEPTOR ANTAGONIST
PREVENTION OF VOMITING

ROUTE (list)

ORAL

ATC code

PK parameters

Tmax 2 HOUR
VD 1956 LITER
Cl 41.7 LITER / HOUR
PPB 96 PERCENT
t1/2 34 HOUR

Solubility

PRACTICALLY INSOLUBLE IN WATER

Target

TARGET SUBSTANCE P/NEUROKININ 1 (NK1) RECEPTOR

Download SDF file

Methanone, [2-[1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-(4-pyridinyl)-1H-1,2,3-triazol-4-yl]-3-pyridinyl](2-chlorophenyl)-

Formula:
C28H16ClF6N5O

Calculated chemical properties:

MW 587.91
NB_atoms 41
XLogP 7.37
PSA 57.703
NB_HD 0
NB_HA 6
fsp3 0.11
Lipinski(0=no;1=yes) 0

FDA
NDA 220152 (label) INN (TRADIPITANT) NEREUS (VANDA PHARMS INC) APPROVAL= AP YEAR= 2025 NEWMOLECULARENTITY